ID A0Z5N0_9GAMM Unreviewed; 390 AA.
AC A0Z5N0;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Epoxide hydrolase-like protein {ECO:0000313|EMBL:EAW40640.1};
GN ORFNames=MGP2080_12988 {ECO:0000313|EMBL:EAW40640.1};
OS marine gamma proteobacterium HTCC2080.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247639 {ECO:0000313|EMBL:EAW40640.1, ECO:0000313|Proteomes:UP000004719};
RN [1] {ECO:0000313|EMBL:EAW40640.1, ECO:0000313|Proteomes:UP000004719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2080 {ECO:0000313|EMBL:EAW40640.1,
RC ECO:0000313|Proteomes:UP000004719};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
CC -!- SIMILARITY: Belongs to the peptidase S33 family.
CC {ECO:0000256|ARBA:ARBA00010088}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW40640.1}.
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DR EMBL; AAVV01000007; EAW40640.1; -; Genomic_DNA.
DR AlphaFoldDB; A0Z5N0; -.
DR ESTHER; 9gamm-a0z5n0; Epoxide_hydrolase.
DR eggNOG; COG0596; Bacteria.
DR OrthoDB; 9780765at2; -.
DR Proteomes; UP000004719; Unassembled WGS sequence.
DR GO; GO:0016803; F:ether hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000639; Epox_hydrolase-like.
DR InterPro; IPR010497; Epoxide_hydro_N.
DR InterPro; IPR016292; Epoxide_hydrolase.
DR PANTHER; PTHR21661:SF35; EPOXIDE HYDROLASE; 1.
DR PANTHER; PTHR21661; EPOXIDE HYDROLASE 1-RELATED; 1.
DR Pfam; PF06441; EHN; 1.
DR PIRSF; PIRSF001112; Epoxide_hydrolase; 1.
DR PRINTS; PR00412; EPOXHYDRLASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EAW40640.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000004719}.
FT DOMAIN 5..110
FT /note="Epoxide hydrolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06441"
FT ACT_SITE 179
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
FT ACT_SITE 310
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
FT ACT_SITE 362
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001112-1"
SQ SEQUENCE 390 AA; 44141 MW; BF225FD1BD5E19E5 CRC64;
MESPITPFTP SLDDAAIADL KRRLELTRYP DEETVEDWSQ GVPLAYVREL TDYWVSQYDM
TRVSNTLNNW PNFQTEIEGL DIHFIYQRSP HTNATPLLLT HGWPGSVLEF RHLIDRLSNP
TEHGGSAENA FHVVVPALPG YGFSGKPRAA GTSVQKIADL WIALMQRLGH AKFLAHGGDW
GSLVTQAIAT APNTPCAGIH ITLPVVAPDP ETLESLLPEE VKALEAFNFY QDWDSGYSKQ
QSTRPQTLGY GLADSPTGQM AWIIEKYAQW CDCEVNGLRH PENAINRDEL LDTVMLYWLT
NTGASSARLY WESFNNPDMS EVQLSTAISL FPNEIFRSSE RWARKKFINL HYFNDQIAKG
GHFSALEVPD ILAHELWQWR EQLRSREILG
//
