ID   A0Z6R2_9GAMM            Unreviewed;       529 AA.
AC   A0Z6R2;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   24-JAN-2024, entry version 45.
DE   RecName: Full=Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 {ECO:0000256|ARBA:ARBA00040298};
GN   ORFNames=MGP2080_04810 {ECO:0000313|EMBL:EAW40290.1};
OS   marine gamma proteobacterium HTCC2080.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX   NCBI_TaxID=247639 {ECO:0000313|EMBL:EAW40290.1, ECO:0000313|Proteomes:UP000004719};
RN   [1] {ECO:0000313|EMBL:EAW40290.1, ECO:0000313|Proteomes:UP000004719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTCC2080 {ECO:0000313|EMBL:EAW40290.1,
RC   ECO:0000313|Proteomes:UP000004719};
RX   PubMed=20472793; DOI=10.1128/jb.00511-10;
RA   Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA   Giovannoni S.J.;
RT   "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT   OM60/NOR5 clade of the Gammaproteobacteria.";
RL   J. Bacteriol. 192:3842-3843(2010).
CC   -!- FUNCTION: Probable oxidoreductase that may play a role as regulator of
CC       mitochondrial function. {ECO:0000256|ARBA:ARBA00037217}.
CC   -!- SUBUNIT: Interacts with COX5B; this interaction may contribute to
CC       localize PYROXD2 to the inner face of the inner mitochondrial membrane.
CC       {ECO:0000256|ARBA:ARBA00038825}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix
CC       {ECO:0000256|ARBA:ARBA00004305}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAW40290.1}.
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DR   EMBL; AAVV01000009; EAW40290.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0Z6R2; -.
DR   eggNOG; COG1233; Bacteria.
DR   OrthoDB; 9774675at2; -.
DR   Proteomes; UP000004719; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR   InterPro; IPR002937; Amino_oxidase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   PANTHER; PTHR10668; PHYTOENE DEHYDROGENASE; 1.
DR   PANTHER; PTHR10668:SF103; PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF01593; Amino_oxidase; 1.
DR   SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000004719}.
FT   DOMAIN          15..290
FT                   /note="Amine oxidase"
FT                   /evidence="ECO:0000259|Pfam:PF01593"
SQ   SEQUENCE   529 AA;  57129 MW;  0BF24C61268EA47E CRC64;
     MTAYDTIIIG GGHNGLTTAA YLARAGQRVC VLERRPVVGG AAVTEEFHPG YRNSVFSYVV
     SLLRPEVVKD LELERYGYQP IPLDNSLYLD SIGEYLLLTG DEAHDRAQFA KFSSTDYEAY
     LAFEEVVDQV GGLLAKQWLK EPPRLGDQGV SDLISMLKLG VDVFRLDAES RWRLMQFFIG
     APETIIDRWF ESPKVKAMVA AHIMPANYAP LSQPGASLAM LHHAVGEIAG RKGAWGLVKG
     GMGSITQAMA QSGQAHGVEI RTDASVARIN VDGGRVCGVT LESGEVIRAP TVAANTDPKR
     TFLKLLGAEH LPASFARDIG AFRQESASLR MNLALSELPH FAALPGGGQL GPHHRASITL
     IESAAHLNEA FHSARSGVPA NPPIIEAIIP STIDPDLVDK PGHHVMSLLC KYMPYTLSDG
     QSWDDRKPAV VAQILDYLER FIPDVTRILV GHQCMTPLDL ERVLGLTGGD ICHGRLEPDQ
     LFNMRPHPDA AQYATPVPGL YLCGSGAHPG GGVTGAPGHN AAQRILRDL
//