ID A0ZAW3_NODSP Unreviewed; 882 AA.
AC A0ZAW3;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=DNA methylase N-4/N-6 {ECO:0000313|EMBL:AHJ30373.1};
GN ORFNames=NSP_40730 {ECO:0000313|EMBL:AHJ30373.1};
OS Nodularia spumigena CCY9414.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC Nodularia.
OX NCBI_TaxID=313624 {ECO:0000313|EMBL:AHJ30373.1, ECO:0000313|Proteomes:UP000019325};
RN [1] {ECO:0000313|EMBL:AHJ30373.1, ECO:0000313|Proteomes:UP000019325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCY9414 {ECO:0000313|EMBL:AHJ30373.1};
RX PubMed=23555932;
RA Voss B., Bolhuis H., Fewer D.P., Kopf M., Moke F., Haas F., El-Shehawy R.,
RA Hayes P., Bergman B., Sivonen K., Dittmann E., Scanlan D.J., Hagemann M.,
RA Stal L.J., Hess W.R.;
RT "Insights into the physiology and ecology of the brackish-water-adapted
RT Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome
RT analysis.";
RL PLoS ONE 8:E60224-E60224(2013).
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DR EMBL; CP007203; AHJ30373.1; -; Genomic_DNA.
DR AlphaFoldDB; A0ZAW3; -.
DR STRING; 313624.NSP_40730; -.
DR REBASE; 81860; M.Nsp9414ORF40730P.
DR PATRIC; fig|313624.11.peg.4086; -.
DR eggNOG; COG0863; Bacteria.
DR HOGENOM; CLU_015672_0_0_3; -.
DR Proteomes; UP000019325; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR GO; GO:0009307; P:DNA restriction-modification system; IEA:InterPro.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR InterPro; IPR002941; DNA_methylase_N4/N6.
DR InterPro; IPR011335; Restrct_endonuc-II-like.
DR InterPro; IPR007560; Restrct_endonuc_IV_Mrr.
DR InterPro; IPR001091; RM_Methyltransferase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF04471; Mrr_cat; 1.
DR Pfam; PF01555; N6_N4_Mtase; 1.
DR PRINTS; PR00508; S21N4MTFRASE.
DR SUPFAM; SSF52980; Restriction endonuclease-like; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:AHJ30373.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 43..336
FT /note="DNA methylase N-4/N-6"
FT /evidence="ECO:0000259|Pfam:PF01555"
FT DOMAIN 743..814
FT /note="Restriction endonuclease type IV Mrr"
FT /evidence="ECO:0000259|Pfam:PF04471"
SQ SEQUENCE 882 AA; 101221 MW; 8C4A4585C541A391 CRC64;
MQKMSTLENF KNISCNPYYL TNLGAAYLGN SLALMAELPN ESVDLICTSP PFALVRKKEY
GNVDACEYIE WFKKFAIQFY RILKPQGSLV VDIGGTWHKG VPVRSLYHFE LVVELCKPKS
KGGLGFYLAQ ELFWYNPAKL PTPAEWVTVR RERVKDAVNT VWWLSKDPHP KANNKRVLRP
YSDAMKNLLK NGYEAKLRPS GHDISTKFKN DRGGAIPPNI IIDSEFGSST LIGKPVLGEF
NWILENDMVQ PVNVISASNT ASNDYYQRRC KEEGVKPHPA RFPQALPEFV IGLCTEPGDL
VLDPFAGSNT TGRVAETLDR RWLAFELDEN YIQTSQFRFE NDAPLVVTPL VDKKALKTKA
LQLAPDAIKI SPEIHAQDTP YQLDLFQLHN SKMADQKLKF TYGHQFTPKK MKLPDLVELC
ISYQPDRRAL EDAISRKYYS NHSTQNNSQQ EDNRSKLSMN TFLSLRAYKL VESIGDDMWQ
YQVSNLSNEL LENQDNPKEV KKIFARHILT NLTGMSLLKA IEAINSRGDK PKLDLIGYEL
QEMGYSLSPN AIYASTMRQW LQEAGIFEKT DQINWDQVYD ILELDKDYID ELYTLTSGQK
YFLLAMLQMS ITDFTKWNDI VNYATSVYKV RFPSKSFVKD IIQPLTDAEL IETEKTTGGR
GAKPNLVKLT EKAQKELLSK LLESIADMTE ISQTELNRSF EDVVQDLDHA DKHIKGKALE
LLAIWMIRLT SLRFTKWRKR DYETGQGEVD VLAASDRFVY HRWQIQCKNT KRVDVEVLAK
EVGMTFVTGA DVVMIVTTGE FTRDAFQYAY RMMEVSRYYM VLIQKEDIES IKEDKTNIIK
ILDKRARRVF AKKELGMIDE EIDELEVEEA SLTDFDGELE ED
//
