ID A1A2R2_BIFAA Unreviewed; 1589 AA.
AC A1A2R2;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE RecName: Full=Activase {ECO:0008006|Google:ProtNLM};
GN Name=yxcA {ECO:0000313|EMBL:BAF39995.1};
GN OrderedLocusNames=BAD_1214 {ECO:0000313|EMBL:BAF39995.1};
OS Bifidobacterium adolescentis (strain ATCC 15703 / DSM 20083 / NCTC 11814 /
OS E194a).
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=367928 {ECO:0000313|EMBL:BAF39995.1, ECO:0000313|Proteomes:UP000008702};
RN [1] {ECO:0000313|EMBL:BAF39995.1, ECO:0000313|Proteomes:UP000008702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15703 / DSM 20083 / NCTC 11814 / E194a
RC {ECO:0000313|Proteomes:UP000008702};
RA Suzuki T., Tsuda Y., Kanou N., Inoue T., Kumazaki K., Nagano S., Hirai S.,
RA Tanaka K., Watanabe K.;
RT "Bifidobacterium adolescentis complete genome sequence.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; AP009256; BAF39995.1; -; Genomic_DNA.
DR STRING; 367928.BAD_1214; -.
DR PaxDb; 1680-BADO_1653; -.
DR KEGG; bad:BAD_1214; -.
DR HOGENOM; CLU_002393_1_0_11; -.
DR Proteomes; UP000008702; Chromosome.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 4.
DR InterPro; IPR002731; ATPase_BadF.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR018709; CoA_activase_DUF2229.
DR InterPro; IPR008275; CoA_E_activase_dom.
DR NCBIfam; TIGR00241; CoA_E_activ; 1.
DR PANTHER; PTHR32329:SF4; ACTIVATOR OF 2-HYDROXYACYL-COA DEHYDRATASE-RELATED; 1.
DR PANTHER; PTHR32329; BIFUNCTIONAL PROTEIN [INCLUDES 2-HYDROXYACYL-COA DEHYDRATASE (N-TER) AND ITS ACTIVATOR DOMAIN (C_TERM)-RELATED; 1.
DR Pfam; PF01869; BcrAD_BadFG; 2.
DR Pfam; PF09989; DUF2229; 1.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000008702}.
FT DOMAIN 27..285
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 358..612
FT /note="ATPase BadF/BadG/BcrA/BcrD type"
FT /evidence="ECO:0000259|Pfam:PF01869"
FT DOMAIN 732..950
FT /note="DUF2229"
FT /evidence="ECO:0000259|Pfam:PF09989"
FT REGION 1076..1096
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1130..1148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1589 AA; 173902 MW; 5C02C182DAB74D97 CRC64;
MRTIEVQYMV EAAVTADNTC DTKPLRVGLD IGSTTVKAVV LDQTDSLDAV LFSDYRRHHA
NVRATVAGLL EDIHKELEAR GRGDEPIRLA ITGSGGLALA DNLHVPFVQE VIAETRAIDE
EYPQADVIIE LGGEDAKITY LKPTPEQRMN GSCAGGTGAF IDQMATLLDT DAAGLNDMAK
HYETLYPIAS RCGVFAKTDL QPLINDGAAK PDLAASIFTA VATQTIAGLA SGRPIHGTVI
FLGGPLFFMS ELREAFHRAL EDKVDEFIVP TDAHLYVAFG SALLAGEPDQ LEEGQHFEAR
TCADILKSLE DLKNLPANTP TMPPLFPTEA DREAFNKRHH REHVHIGTLE GAQGPHFLGI
DAGSTTIKAT LVNDDREIVW SSYATNEGSP LTAAVNIVKQ IQSQLPEGAW IARSCATGYG
EGLITTGLHL DEGVVETMAH YRGAEMVSPG VTAVIDIGGQ DMKYLAISDG VIDSIAVNEA
CSSGCGSFLQ TFAQSMGLTI EEFTQAALNS THPVDLGSRC TVFMNSSVKQ AQKEGASMED
IAAGLCYSVV RNALYKVIKL RDSGELGDTV VVQGGTFLND AVLRAFELLT EREVTRPNIA
GLMGAYGAAL TARMHYTDIA DGLDDGDADA DGGKTVDIDG VTHTASSIVS GSDLDNLSMT
TERDVCKLCQ NHCKLTITTF QDGSRYVTGN RCERGGDSKK QRSDRPNLYD YKYKRCFAYR
RLTDKKATRG EIGIPRVLNM YENYPFWFTL LTSLGFKVMI SGRSSHELFE TGIESIASEN
ICYPAKLVHG HIKWLLNKGI KTIFYPCVSY EENFVPNTDN HYNCPVVANY PVVIGANMPE
LREEGVRYMR PYFNMANHEL MVDRIVEEFA WANVTREEAE TAVKAAYAEN EVFKHDVQME
GLKALAYMKE HDCKGIVLAG RPYHVDPEIN HGIPETICAL GMVVLSEDSI CELQPGEKLN
LSEFLAEGEE DPRKKNANGF RHVDDRKVTK MPLRVTNQWA YHARLYAAAH FVASYPGLEL
VQLNSFGCGL DAITTDQVSE ILADKADVYT MLKIDEVSNL GAAKIRLRSL KAAVEERERN
KKNDGFRKTG TEAPTPGRQV MLDTVMKANP KLTEAVTAAS KRAAENGKGE SQETAKTQTN
GKGASAHNSA TLSKYANRIP FGKNMKDYTI VAPQMSPIHF SLVESVIRSG GYKFDILEHA
SREDVETGLK YVNNDACYPA IMVIGQLVDA ILEGKYDPDH TALAITQTGG MCRATNYFGL
IRKALVDAGY PQIPVIAIST QGIEDNPGFT ATPALLHRAV KALIIGDLLM KCLYRVRPYE
VTPGSANKLY ETWDTIVRET LENHGRSKTA RKFIGKGYLP YPTLVKEIVK SFDSLPLKDE
PRKVRVGVVG EILVKYQPDA NNHVVDVIES QDCEAVVPGI MEFMTTRPYI SDWNEHYLGM
GGSKIGYALM RKGLDLYNAP VREAIDLAHG KFSQDLPMPE LVKKADEVTS VGVQAGEGWL
LTAEILELIE SGCPNVVCAQ PFACLPNHVT GRGMFGKIRR LHPEANIVSI DYDPGASEAN
QLNRIKLMIS AAKKAHRAAE EARNSEKAA
//
