ID A1C5C9_ASPCL Unreviewed; 613 AA.
AC A1C5C9;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=RNA binding protein (Arp), putative {ECO:0000313|EMBL:EAW14897.1};
GN ORFNames=ACLA_003080 {ECO:0000313|EMBL:EAW14897.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW14897.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW14897.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the RRM TET family.
CC {ECO:0000256|ARBA:ARBA00008448}.
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DR EMBL; DS027004; EAW14897.1; -; Genomic_DNA.
DR RefSeq; XP_001276323.1; XM_001276322.1.
DR AlphaFoldDB; A1C5C9; -.
DR STRING; 344612.A1C5C9; -.
DR EnsemblFungi; EAW14897; EAW14897; ACLA_003080.
DR GeneID; 4708466; -.
DR KEGG; act:ACLA_003080; -.
DR VEuPathDB; FungiDB:ACLA_003080; -.
DR eggNOG; KOG4198; Eukaryota.
DR HOGENOM; CLU_022834_2_0_1; -.
DR OMA; NLDRYVV; -.
DR OrthoDB; 228305at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0140453; C:protein aggregate center; IEA:EnsemblFungi.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071502; P:cellular response to temperature stimulus; IEA:EnsemblFungi.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR GO; GO:0031445; P:regulation of heterochromatin formation; IEA:EnsemblFungi.
DR CDD; cd06133; ERI-1_3'hExo_like; 1.
DR CDD; cd12452; RRM_ARP_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR InterPro; IPR047201; ERI-1_3'hExo-like.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR034351; Nrp1_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR034870; TET_fam.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR23238:SF31; GH13594P-RELATED; 1.
DR PANTHER; PTHR23238; RNA BINDING PROTEIN; 1.
DR Pfam; PF00929; RNase_T; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00641; zf-RanBP; 2.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 2.
DR PROSITE; PS50199; ZF_RANBP2_2; 2.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00176}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00322}.
FT DOMAIN 253..331
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 352..381
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 426..457
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 593..613
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 613 AA; 65715 MW; 696B23386740720D CRC64;
MATVSAPTPK LDRYIVIHVA TTCDEHGVYV TKDSAEVIEL GWILLDTKTC EELHRESVLV
KPVNTPITPL CTSLTTLTWE HVRSAGTFRD AINRFDAFAQ EHLISKNLEF AFVTLDSWDL
RVQLPREARD KAVVLPPYLQ HSRTFDLRTE YQRWQTHHPE SLPFGPSSLS NICAALEVEP
VQSSAPIKHN LPFHLQALAP ASPRRAMEEA ITLARVLRGL IRKSQPPHEH PEILTRPMDA
RADVRAFLTE RSKVLHLSGL PHDTTQSELE SWFTQFGGRP IAFWTLRTPD QHKPTGTGFA
VFSSHEEAAE SLCMNGRALN EKAIEVSPSS SRVLDRAAEI LTPFPPSKNR PRPGDWTCPS
CGFSNFQRRT ACFRCSFPAM AAAPDPMGYG AYGYGPPSMM PPHMGHNHGM GHSRGLGGNG
GVVPFRAGDW KCGSEGCGYH NFAKNINCLR CGAPRSGAAV VADSAFPSPM DPPAGFGMGP
NSMTSTPAPA PFTSAAGGFG GFSQQFAAPP NNYALPSGLG SAPGAYPPMG QVNAGYGSTN
ASHTASSFSN PATQAAFSGA DHASSTSASN GAFYGTDGSN DPFAFLSTGL GGLTVSDDSH
SRRNGTGASK SPA
//
