ID A1CMI5_ASPCL Unreviewed; 682 AA.
AC A1CMI5;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=Glycosyltransferase {ECO:0000313|EMBL:EAW08772.1};
GN ORFNames=ACLA_097070 {ECO:0000313|EMBL:EAW08772.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW08772.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW08772.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase group 1 family.
CC Glycosyltransferase 4 subfamily. {ECO:0000256|ARBA:ARBA00009481}.
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DR EMBL; DS027058; EAW08772.1; -; Genomic_DNA.
DR RefSeq; XP_001270198.1; XM_001270197.1.
DR AlphaFoldDB; A1CMI5; -.
DR STRING; 344612.A1CMI5; -.
DR EnsemblFungi; EAW08772; EAW08772; ACLA_097070.
DR GeneID; 4702153; -.
DR KEGG; act:ACLA_097070; -.
DR VEuPathDB; FungiDB:ACLA_097070; -.
DR eggNOG; KOG0853; Eukaryota.
DR HOGENOM; CLU_011001_2_0_1; -.
DR OMA; KKAVIHW; -.
DR OrthoDB; 5474650at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03792; GT4_trehalose_phosphorylase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR001296; Glyco_trans_1.
DR InterPro; IPR049438; TreT_GT1.
DR PANTHER; PTHR47779; SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED; 1.
DR PANTHER; PTHR47779:SF1; SYNTHASE (CCG-9), PUTATIVE (AFU_ORTHOLOGUE AFUA_3G12100)-RELATED; 1.
DR Pfam; PF00534; Glycos_transf_1; 1.
DR Pfam; PF21269; TreT_GT1; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 239..398
FT /note="Trehalose synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21269"
FT DOMAIN 457..631
FT /note="Glycosyl transferase family 1"
FT /evidence="ECO:0000259|Pfam:PF00534"
SQ SEQUENCE 682 AA; 77262 MW; 4D58C68976F5022A CRC64;
MTMQVYASSI HQFQRKISQH QKKKWQESQK QGAWFGPTSE EPNQIRYAGI TAKKIDEHNL
TIVIAVRDVV YPLDFLEHHF HVPERNLDTS ITDFVLEQLR KYSANHTEKF VGACLTTELT
EKCPRLAPRL WLELDVMPLV IPQRDALGGR YEQEAPWETR EADEQAEYLA MKCVRLFGPN
NIPLLQVGFR GLVEVDSGFL MHFATLEDYR RTSSEETWVA LEHFAARVRE KRVRIAIFGA
TPQGGGVALM RHAFLRLSQL LGLDIQWYVP QPRSGVFRIT KMNHNIFQGV AKPDDYLSAS
DEETLRKWVS VNSQRSWSTS GGPLDHPSHG GADIVVVDDP QLTDLIPIAK EKAPSRPVIF
RSHIQIRTDL TCTPGTPQAR SWDWLWQRAK QADVFVSHPI SESIPPTVPK EMVAYSPAST
DLLDGLNKQM EDCDTAYYGR LFNQWCHKTG VPMVNYPDEE YFVQIARFDP SKGILDVLDS
YAKFHDRLTK SMPEAKIPKL VICGHGSVDD PDASVMFDTT MSHIHEEMPQ LADKIAVVRA
SPSDQVLNAI LSKSKVVLQL STREGFEIKV SEALHKAKPV IVTRVGGLPY QVTDGETGFV
VDMNDTDRVA ECLYNLWTDE ELYAKMRTNA PRSLSDNVTT VGLVSSWLYL IWMLFENPSW
RPRNQLLSDL MLKDLGLASG GS
//
