ID A1CQ97_ASPCL Unreviewed; 518 AA.
AC A1CQ97;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Pre-mRNA splicing factor (Prp31), putative {ECO:0000313|EMBL:EAW07818.1};
GN ORFNames=ACLA_025350 {ECO:0000313|EMBL:EAW07818.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW07818.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW07818.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the PRP31 family.
CC {ECO:0000256|ARBA:ARBA00005572}.
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DR EMBL; DS027059; EAW07818.1; -; Genomic_DNA.
DR RefSeq; XP_001269244.1; XM_001269243.1.
DR AlphaFoldDB; A1CQ97; -.
DR STRING; 344612.A1CQ97; -.
DR EnsemblFungi; EAW07818; EAW07818; ACLA_025350.
DR GeneID; 4702094; -.
DR KEGG; act:ACLA_025350; -.
DR VEuPathDB; FungiDB:ACLA_025350; -.
DR eggNOG; KOG2574; Eukaryota.
DR HOGENOM; CLU_026337_2_0_1; -.
DR OMA; IGNGPMD; -.
DR OrthoDB; 4493115at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IEA:EnsemblFungi.
DR GO; GO:0000244; P:spliceosomal tri-snRNP complex assembly; IEA:InterPro.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR InterPro; IPR027105; Prp31.
DR InterPro; IPR019175; Prp31_C.
DR PANTHER; PTHR13904; PRE-MRNA SPLICING FACTOR PRP31; 1.
DR PANTHER; PTHR13904:SF0; U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF09785; Prp31_C; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 172..290
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 288..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 459..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..33
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 55508 MW; 3CFB6F7A4EB6E951 CRC64;
MSNAEELLRD FESDDEDFQA GEEIEEDVDE EALQQPAPEI TNEFDVAVST TDELTRLHKS
LRDHYSIRFP ELETLVTNPI DYAKTVAILK NGPLNDIKAL STSADNMVGA PLRSILDGPS
LMVVAVEGTT TRGREMTESE LQAVLDTCER ILKLDRERTA LTQSIQSRMS QIAPNLAALI
GPETAAQFLN QTGGLRELAK IPACNLAAQG SKRTEGLGFA TNIGIRSQGF LYHSPIIEDI
PNDLKKQAMR IVSAKMVLAT RADVSQYSPD GSLGEELKQQ CYQRLEKLTE PAPNSGVKAL
PAPDDKPSRK RGGRRARKAK EAVAMTELRK AQNRLAFGKE EAEVGYGTGE GTVGLGMLGQ
QNDGRIRATQ IDQRTRAKLS KSNKGWGAAT PVGGTASSLR GFGSGAGGTA SVLQAKGLRT
SGVGTSLAGT AGTASTIAFT PVQGLELVDP KVQAELQRKR KAEEDRWFKS GTFTQVGGQS
NSTKTGENGG FKVPPLPARK KVDTGEGKMA PPPPPVKP
//
