ID A1CW60_NEOFI Unreviewed; 530 AA.
AC A1CW60;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Sorting nexin 3 {ECO:0000313|EMBL:EAW24862.1};
GN ORFNames=NFIA_103500 {ECO:0000313|EMBL:EAW24862.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW24862.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027685; EAW24862.1; -; Genomic_DNA.
DR RefSeq; XP_001266759.1; XM_001266758.1.
DR AlphaFoldDB; A1CW60; -.
DR STRING; 331117.A1CW60; -.
DR EnsemblFungi; EAW24862; EAW24862; NFIA_103500.
DR GeneID; 4594147; -.
DR KEGG; nfi:NFIA_103500; -.
DR VEuPathDB; FungiDB:NFIA_103500; -.
DR eggNOG; KOG2273; Eukaryota.
DR HOGENOM; CLU_014571_2_0_1; -.
DR OMA; YWESFLP; -.
DR OrthoDB; 1891044at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IEA:EnsemblFungi.
DR GO; GO:0005628; C:prospore membrane; IEA:EnsemblFungi.
DR GO; GO:0030904; C:retromer complex; IEA:EnsemblFungi.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0032120; P:ascospore-type prospore membrane formation; IEA:EnsemblFungi.
DR GO; GO:0006886; P:intracellular protein transport; IEA:EnsemblFungi.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:EnsemblFungi.
DR CDD; cd07627; BAR_Vps5p; 1.
DR CDD; cd06861; PX_Vps5p; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR035803; BAR_Vps5.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR037868; PX_Vps5.
DR InterPro; IPR015404; Vps5_C.
DR PANTHER; PTHR10555:SF170; FI18122P1; 1.
DR PANTHER; PTHR10555; SORTING NEXIN; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF09325; Vps5; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT DOMAIN 123..239
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 1..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 411..438
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 7..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 58587 MW; 95EC817D5E1443B6 CRC64;
MCPRSQVMVH RERKLKKSAT KLEAVDDTVD PLGPLGDKPT DSLAPVNEQA PTPPQKEPFA
GRGARPTSST SQTSSAGGLG DSVHLEEDGA GFRGPPPVQP PADADGAKRQ SQPSVSIEEA
AKPTFEITVG DPHKVGDLTS SHIVYQVRTK TTSKAYRQPE FTVSRRYRDF LWLYNSMHNN
NPGVVVPPPP EKQAVGRFDT NFVESRRAAL ERMLNKIAAH PILQHDADLK IFLESESFNM
DVKNKENREP DLGQNKGMFS SFGISVGGGG KFVEHDDWFH DRKIYMDALE NQLKALLKAI
DVVVAQRKGL AEAAGDFSSS LHALAAVELS PALSSPLDGL SELQLRIKEL YERQAQQDVL
TLGITIDEYL RIIGSVKTAF SQRQKAFHSW HAAESELQKR KHTQEKLLRQ GKTQQDRLNQ
ANADVADAER KVHQARLLFD DMGRLMRNEL QRFEKEKVED FKSGVETFLE SAVEAQKELI
ELWETFLLQL DAGEEGIPFF APPPVATNAP AQQATDEASG TAPVAAEETA
//
