ID A1CZY0_NEOFI Unreviewed; 1382 AA.
AC A1CZY0;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE RecName: Full=Telomeric single stranded DNA binding POT1/Cdc13 domain-containing protein {ECO:0000259|SMART:SM00976};
GN ORFNames=NFIA_038740 {ECO:0000313|EMBL:EAW24300.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW24300.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027686; EAW24300.1; -; Genomic_DNA.
DR RefSeq; XP_001266197.1; XM_001266196.1.
DR EnsemblFungi; EAW24300; EAW24300; NFIA_038740.
DR GeneID; 4592956; -.
DR KEGG; nfi:NFIA_038740; -.
DR VEuPathDB; FungiDB:NFIA_038740; -.
DR eggNOG; ENOG502SAAT; Eukaryota.
DR HOGENOM; CLU_261220_0_0_1; -.
DR OMA; VWPYSSS; -.
DR OrthoDB; 2688420at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR CDD; cd04497; hPOT1_OB1_like; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR Pfam; PF02765; POT1; 1.
DR SMART; SM00976; Telo_bind; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT DOMAIN 1151..1283
FT /note="Telomeric single stranded DNA binding POT1/Cdc13"
FT /evidence="ECO:0000259|SMART:SM00976"
FT REGION 442..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1308..1382
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 496..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..565
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 589..615
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 627..644
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 645..722
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 786..800
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..823
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 865..903
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 912..931
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 943..978
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 990..1022
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1348..1374
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1382 AA; 151312 MW; 8418A700E88D720F CRC64;
MSEPLRSTAI SIAQISPDAD RILERSIHAI VTLVWPYSSS NKSLSLLLAE PDFRLRRNNG
QVKVVFRGRA AEAVAKSQVG IGDHVYLGLA GSKFVPSVAV AQTPGKCVPW DVQLDDRVLL
EIWRSSQHFS TVKLDPSTVA AQDTEDVFAP PATPIANGRV ERDEATSAAR FESWRSPAFV
ERTRTSFGGL VDSAYDPFAE ADGFVPGKGR KRPRFSFRGA DWRVVDEPAS PGEKEVPADW
TWMFAEDETH ESDIGGEDHI DSATIPQEIS TVTATVTNAP EGADTVADVD NESLDVGLMS
TERMAEQPTR PSPDFAQPLR APGFPQHFAR QQFASSDFQY PTDTPRLYPI PSPGLPIPSP
LVTRSSSAHD YFPTVASNVQ TPLDQSAADG QDVEMTEKEN IVISRVQPDV PTSQKLQPLV
TTPQQAVARN TWDPTSQNAS IDLEADSQGG MKGTSAADAM PIEDREPAQP PEDVEKQISD
VPLVSLGQSF AEKPAEVASR DIRDVVEEES EQSDINQEKR EVQVEESNED SEDELEEQSE
VEFEEESVEE ESAEEEEDDL VEEYGYEDSQ EQRSQRPPDA FGANDFYQDG TRRYEDSEVE
EIAIGTNRAL EDDDLSDTGS EAFSAADRQA AEERGRPHNM EEESGEDEHE GDYEDEGTFD
EEGIEGGDER AEVLDEEEDE DDEDEEEQEE QEQEDDDEDE DEEESVFEDE QEAYEDDYDR
VDSESESYAG GDSAARPEKV VHPEVIVLDS DSEDEAVVSA PTKAHMPSAE YAATVNDVES
SATSAEEDDV YDRSSVGSEA EEWPEDELAE DDQTGDDKSE EESMQDEIAV RDNAEDELME
DAPSEEDSVA EGPIEVHADA EENSASADPV QSEVQQEADI ENDLISETPN EVLQATSGAP
QSPEGQDIVD LRVSVAQSTQ GPYTDSVSGP RPQDLATDPE LYRLGDTGED ETRSLETDAH
AESGPDKPGL DDEGIREPFF HGAASPQPVD SSAELASPVQ EPSPQAPQLV TPDASQLTAP
SHHLPTAIPV GDFPPTPEQT QEVPQGPSTQ YDGHADAPER TVLHISTTSV ETDVSSTNEY
NVQMSSTLAE HQRQTQTDGV SVHDEEYAMS SVGDEIASEV HDWGVSAQPL KRMSSVVNRD
HPGLRSKYSY FAPLATLIDH YNSLIDTISV VSEVSPISRA TTGKKDFTLS LLVTDPSMAG
TIVHAQIFRP YKSALPSVKE GDAILLRNFQ VKSFNHSMML VSVDTSAWAV FHNASKEAQI
AGPPVEHGDE ETAYAADLRQ WYHEVGIAMV ADYQLQASVL TASREATPVS SVAHSDAGSV
DSASREVRGE SSVSNRGSKR RKSHRRITIH ELRDGRRYAE VGSPSDKESI HELRDGTLYA
NL
//
