ID A1DGG4_NEOFI Unreviewed; 755 AA.
AC A1DGG4;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=20S cyclosome subunit (BimA/Nuc2/Cdc27), putative {ECO:0000313|EMBL:EAW18471.1};
GN ORFNames=NFIA_084230 {ECO:0000313|EMBL:EAW18471.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW18471.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SIMILARITY: Belongs to the APC3/CDC27 family.
CC {ECO:0000256|ARBA:ARBA00038210}.
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DR EMBL; DS027696; EAW18471.1; -; Genomic_DNA.
DR RefSeq; XP_001260368.1; XM_001260367.1.
DR AlphaFoldDB; A1DGG4; -.
DR STRING; 331117.A1DGG4; -.
DR EnsemblFungi; EAW18471; EAW18471; NFIA_084230.
DR GeneID; 4586926; -.
DR KEGG; nfi:NFIA_084230; -.
DR VEuPathDB; FungiDB:NFIA_084230; -.
DR eggNOG; KOG1126; Eukaryota.
DR HOGENOM; CLU_008850_0_1_1; -.
DR OMA; YPETIGV; -.
DR OrthoDB; 152021at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:UniProt.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 4.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR001440; TPR_1.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF13; CELL DIVISION CYCLE PROTEIN 27 HOMOLOG; 1.
DR Pfam; PF00515; TPR_1; 2.
DR Pfam; PF14559; TPR_19; 1.
DR SMART; SM00028; TPR; 8.
DR SUPFAM; SSF81901; HCP-like; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 6.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 73..106
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 462..495
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 530..563
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 564..597
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 598..631
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 700..733
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 137..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 211..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..228
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..379
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 755 AA; 83713 MW; 592598A85780B040 CRC64;
MRCSSPVVYM LTSPERRKRH IYSLSVTFRT VKSKPHTITA GILDREAPTS AAPMSSRKHK
HSETRRQHLP DAAAVFCLLG KLWHAHKDIN KAVECYVESL KLNPFMWDAF QGLCDTGVNV
RVSNIYKMNS ELLAVLSSSP QDDAEPISDK SAQTNGPLQA QANVNPSSDP FASTTSRSDS
GTSHGSSALW EKLNGSTVSV ASSGVPASIV HEGAETPSGQ SSGSDEFRLA NGKNGVDAPW
DPPLAPARKN RTIQAISGEY PMDPPPKMKP TGIRPRTRTR TDPEDQISTQ TDREATIAPR
VGDRKRTVSG QVAHPPTSQP TEPGAPQRRS VRLFNQIKPT TSKLSASALG VKDAREVKKA
KATGTKGRTT TTTMGRVVSG SRKHGSEHHD ADGKDGRSVP SAHTHAISKG TAHERSKEIE
ALTWLLELFS KLASGFFALC RYRCSESIQI FNSLSHGQRE TPWVLAQIGR AYYEQAMYSE
AEKYFYRVKT MAPSRLEDME IYSTVLWHLK NDVELAYLAH ELMETDRLSP QAWCAIGNSF
SHQRDHDQAL KCFKRATQLD PQFAYGFTLQ GHEYVANEEY DKALDAYRHG ISADSRHYNA
WYGLGTVYDK MGKLDFAEQH FRNAASINPT NAVLICCIGL VLEKMNNPKA ALVQYGRACS
LAPHSVLARF RKARALMKLQ ELKLALSELK ILKDMAPDEA NVHYLLGKLY KMLHDKANAI
KHFTTALNLD PKAAQYIKDA MESLDDDEED DEDMS
//
