ID A1DJT2_NEOFI Unreviewed; 280 AA.
AC A1DJT2;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 73.
DE SubName: Full=Aromatic ring-opening dioxygenase, catalytic LigB subunit, putative {ECO:0000313|EMBL:EAW16971.1};
GN ORFNames=NFIA_003260 {ECO:0000313|EMBL:EAW16971.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW16971.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the DODA-type extradiol aromatic ring-opening
CC dioxygenase family. {ECO:0000256|ARBA:ARBA00007581}.
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DR EMBL; DS027697; EAW16971.1; -; Genomic_DNA.
DR RefSeq; XP_001258868.1; XM_001258867.1.
DR AlphaFoldDB; A1DJT2; -.
DR EnsemblFungi; EAW16971; EAW16971; NFIA_003260.
DR GeneID; 4585604; -.
DR KEGG; nfi:NFIA_003260; -.
DR VEuPathDB; FungiDB:NFIA_003260; -.
DR eggNOG; ENOG502SMUE; Eukaryota.
DR HOGENOM; CLU_046582_0_0_1; -.
DR OMA; GARICHP; -.
DR OrthoDB; 63470at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR GO; GO:0008198; F:ferrous iron binding; IEA:InterPro.
DR GO; GO:0016701; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR CDD; cd07363; 45_DOPA_Dioxygenase; 1.
DR Gene3D; 3.40.830.10; LigB-like; 1.
DR InterPro; IPR014436; Extradiol_dOase_DODA.
DR InterPro; IPR004183; Xdiol_dOase_suB.
DR PANTHER; PTHR30096:SF0; 4,5-DOPA DIOXYGENASE EXTRADIOL-LIKE PROTEIN; 1.
DR PANTHER; PTHR30096; UNCHARACTERIZED; 1.
DR Pfam; PF02900; LigB; 1.
DR PIRSF; PIRSF006157; Doxgns_DODA; 1.
DR SUPFAM; SSF53213; LigB-like; 1.
PE 3: Inferred from homology;
KW Dioxygenase {ECO:0000313|EMBL:EAW16971.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 9..264
FT /note="Extradiol ring-cleavage dioxygenase class III enzyme
FT subunit B"
FT /evidence="ECO:0000259|Pfam:PF02900"
SQ SEQUENCE 280 AA; 31196 MW; ED42DE72192C234A CRC64;
MGGSERARAM FFSHGSGPYV LMGNDHQRPL INVLQSHAHI LDNARGIIVF TAHWETTHPH
ISATPNPQLY YDYAGTPGLP QEAFEYRYDA PGDPDLAARI ASTLQAAGFQ PILNTERGWD
HGVFVPLIVM RPQADLPVIQ MSILKGESDE SEAERNLRYG AAMERFRDEG YVFLFSGSSY
HHLAKVLEAL PERMGNGKVD VSTQEFEAEL ERVAAISDAD KRSAILRTWR QFPQSYEAHP
AGKAEHFMPF LIGSGAAGND KGERTQSWEL FGATMSTFVW
//
