GenomeNet

Database: UniProt
Entry: A1DS19_CAVPO
LinkDB: A1DS19_CAVPO
Original site: A1DS19_CAVPO 
ID   A1DS19_CAVPO            Unreviewed;       226 AA.
AC   A1DS19;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   30-AUG-2017, entry version 61.
DE   SubName: Full=Nav1.3 sodium channel protein {ECO:0000313|EMBL:ABK96794.1};
DE   SubName: Full=Sodium voltage-gated channel alpha subunit 3 {ECO:0000313|Ensembl:ENSCPOP00000016383};
DE   Flags: Fragment;
GN   Name=SCN3A {ECO:0000313|Ensembl:ENSCPOP00000016383};
OS   Cavia porcellus (Guinea pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia;
OC   Hystricomorpha; Caviidae; Cavia.
OX   NCBI_TaxID=10141;
RN   [1] {ECO:0000313|EMBL:ABK96794.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Sage D., Salin P., Alcaraz G., Castets F., Giraud P., Mazet B.,
RA   Crest M., Clerc N.;
RT   "Nav1.7 and Nav1.3 are the only TTX-sensitive sodium channels
RT   expressed in the adult guinea pig enteric nervous system.";
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCPOP00000016383, ECO:0000313|Proteomes:UP000005447}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000016383,
RC   ECO:0000313|Proteomes:UP000005447};
RX   PubMed=21993624; DOI=10.1038/nature10530;
RA   Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J.,
RA   Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E.,
RA   Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J.,
RA   Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S.,
RA   Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I.,
RA   Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I.,
RA   Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J.,
RA   Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D.,
RA   Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L.,
RA   Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S.,
RA   Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G.,
RA   Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K.,
RA   Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T.,
RA   Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J.,
RA   Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S.,
RA   Pedersen J.S., Lander E.S., Kellis M.;
RT   "A high-resolution map of human evolutionary constraint using 29
RT   mammals.";
RL   Nature 478:476-482(2011).
RN   [3] {ECO:0000313|Ensembl:ENSCPOP00000016383}
RP   IDENTIFICATION.
RC   STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000016383};
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AAKN02005777; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAKN02005778; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAKN02005779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAKN02005780; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; EF054797; ABK96794.1; -; mRNA.
DR   Ensembl; ENSCPOT00000024759; ENSCPOP00000016383; ENSCPOG00000004367.
DR   eggNOG; ENOG410KCTY; Eukaryota.
DR   eggNOG; COG1226; LUCA.
DR   GeneTree; ENSGT00830000128242; -.
DR   HOGENOM; HOG000231755; -.
DR   OrthoDB; EOG091G00FK; -.
DR   Proteomes; UP000005447; Unassembled WGS sequence.
DR   Bgee; ENSCPOG00000004367; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:ion channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   Pfam; PF00520; Ion_trans; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005447};
KW   Ion channel {ECO:0000313|EMBL:ABK96794.1};
KW   Ion transport {ECO:0000313|EMBL:ABK96794.1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000313|EMBL:ABK96794.1}.
FT   TRANSMEM     85    112       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       33    119       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED      109    150       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:ABK96794.1}.
FT   NON_TER     226    226       {ECO:0000313|EMBL:ABK96794.1}.
SQ   SEQUENCE   226 AA;  25683 MW;  285F2DB44154CF9B CRC64;
     KDYIGDDSHF YVLDGQKDPL LCGNGSDAGH CPEGYICVKA GRNPNYGYTS FDTFSWAFLS
     LFRLMTQDYW ENLYQLTLRA AGKTYMIFFV LVIFLGSFYL VNLILAVVAM AYEEQNQATL
     EEAEQKEAEF QQMLEQLKKQ QEEAQAVAAA SAASRDFSGI GGLGELLESS SEASKLSSKS
     AKEWRNRRKK RRQRDHSEGH NRGEADRFPK SESEDSVKRR SFLFSM
//
DBGET integrated database retrieval system