ID A1E0A0_POLCS Unreviewed; 393 AA.
AC A1E0A0;
DT 02-SEP-2008, integrated into UniProtKB/TrEMBL.
DT 02-SEP-2008, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Chalcone synthase {ECO:0000313|EMBL:ABK92282.2};
GN Name=CHS1 {ECO:0000313|EMBL:ABK92282.2};
OS Polygonum cuspidatum (Japanese knotweed).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC Caryophyllales; Polygonaceae; Polygonoideae; Polygoneae; Polygonum.
OX NCBI_TaxID=83819 {ECO:0000313|EMBL:ABK92282.2};
RN [1] {ECO:0000313|EMBL:ABK92282.2}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=19225805; DOI=10.1007/s00425-009-0899-1;
RA Ma L.Q., Guo Y.W., Gao D.Y., Ma D.M., Wang Y.N., Li G.F., Liu B.Y.,
RA Wang H., Ye H.C.;
RT "Identification of a Polygonum cuspidatum three-intron gene encoding a type
RT III polyketide synthase producing both naringenin and p-
RT hydroxybenzalacetone.";
RL Planta 229:1077-1086(2009).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531,
CC ECO:0000256|RuleBase:RU003633}.
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DR EMBL; EF090604; ABK92282.2; -; mRNA.
DR AlphaFoldDB; A1E0A0; -.
DR SMR; A1E0A0; -.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR018088; Chalcone/stilbene_synthase_AS.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF111; OS04G0103900 PROTEIN; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00441; CHALCONE_SYNTH; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000256|RuleBase:RU003633};
KW Transferase {ECO:0000256|RuleBase:RU003633}.
FT DOMAIN 6..229
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 239..389
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 165
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 393 AA; 43216 MW; 8B1458E6A207400A CRC64;
MAPSVQEIRK AQRAEGPATV LAIGTATPPN CIYQADYPDY YFRVTNSEHM TDLKEKFRRM
CDKSMIEKRY MHLTEEILKE NQNMCAYMAS SLDSRQDMVV SEVPRLGKEA AQKAIKEWGQ
PKSKITHVIM CTTSGVDMPG ADYQLTKLLG LRPSVKRFMM YQQGCFAGGT ALRLAKDLAE
NTKGARVLVV CSEITAICFR GPTDTHLDSM VGQALFGDGA GAVIIGADPD LSIERPIFEL
VWTAQTILPD SEGAIDGHLR EVGLTFHLLK DVPGLISKNI EKSLTEAFSP LNISDWNSLF
WIAHPGGPAI LDQVEAKLGL KEEKLKATRQ VLNDYGNMSS ACVLFIMDEM RKKSLENGHA
TTGEGLDWGV LFGFGPGLAV ETVVLHSVPV AHH
//
