ID A1K8K8_AZOSB Unreviewed; 388 AA.
AC A1K8K8;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Nitrogen assimilation regulatory protein {ECO:0000313|EMBL:CAL95163.1};
GN Name=nac {ECO:0000313|EMBL:CAL95163.1};
GN OrderedLocusNames=azo2546 {ECO:0000313|EMBL:CAL95163.1};
OS Azoarcus sp. (strain BH72).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=418699 {ECO:0000313|EMBL:CAL95163.1, ECO:0000313|Proteomes:UP000002588};
RN [1] {ECO:0000313|EMBL:CAL95163.1, ECO:0000313|Proteomes:UP000002588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BH72 {ECO:0000313|EMBL:CAL95163.1,
RC ECO:0000313|Proteomes:UP000002588};
RX PubMed=17057704; DOI=10.1038/nbt1243;
RA Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J.,
RA Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C.,
RA Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J.,
RA Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
RT "Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp.
RT strain BH72.";
RL Nat. Biotechnol. 24:1385-1391(2006).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
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DR EMBL; AM406670; CAL95163.1; -; Genomic_DNA.
DR AlphaFoldDB; A1K8K8; -.
DR STRING; 62928.azo2546; -.
DR KEGG; azo:azo2546; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_6_5_4; -.
DR Proteomes; UP000002588; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR CDD; cd08433; PBP2_Nac; 1.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30293:SF0; NITROGEN ASSIMILATION REGULATORY PROTEIN NAC; 1.
DR PANTHER; PTHR30293; TRANSCRIPTIONAL REGULATORY PROTEIN NAC-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR PRINTS; PR00039; HTHLYSR.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000002588};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 91..148
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
SQ SEQUENCE 388 AA; 41936 MW; F4D3919A6B4217F6 CRC64;
MGMEYVVVVI EGRVRSVGAA GPYAAGKAAP DASRRTRAAA DAAPRMTTAR ARESVPIMGQ
APAADRLPAR YQLCRFAIAD PLTAARYTAR MDLKQLEYFV RVAELGSFTR ASIALDIAQP
ALSRQVRLLE VELHQNLLVR NGRGVTLTEA GKVLLEHSRG VLHQIERIRE ELERVRGTPS
GRVAVGLPPS LSRVLTVPVT REFRARMPGA TLSITEGLSV TMREALMNGR LDIALLYNAV
PSTDIDLFPL LDEPLFLVQR ADHGSTAPIP LRELADHPLV IPSRPNALRM LVETELANLG
CRPRIAIEID GVAPILGLVA DGLGSAVLSM NAVATSAKAA EFVVRPFIEP GLQSRLSMAV
SSRRPTTGTQ QAMLELLREI APRLITPA
//
