ID A1S2K7_SHEAM Unreviewed; 529 AA.
AC A1S2K7;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 92.
DE SubName: Full=Drug resistance transporter, EmrB/QacA family protein {ECO:0000313|EMBL:ABL98613.1};
GN OrderedLocusNames=Sama_0403 {ECO:0000313|EMBL:ABL98613.1};
OS Shewanella amazonensis (strain ATCC BAA-1098 / SB2B).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=326297 {ECO:0000313|EMBL:ABL98613.1, ECO:0000313|Proteomes:UP000009175};
RN [1] {ECO:0000313|EMBL:ABL98613.1, ECO:0000313|Proteomes:UP000009175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1098 / SB2B {ECO:0000313|Proteomes:UP000009175};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Fredrickson J.,
RA Richardson P.;
RT "Complete sequence of Shewanella amazonensis SB2B.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP000507; ABL98613.1; -; Genomic_DNA.
DR RefSeq; WP_011758523.1; NC_008700.1.
DR AlphaFoldDB; A1S2K7; -.
DR STRING; 326297.Sama_0403; -.
DR KEGG; saz:Sama_0403; -.
DR eggNOG; COG2814; Bacteria.
DR HOGENOM; CLU_000960_28_0_6; -.
DR OrthoDB; 9812221at2; -.
DR Proteomes; UP000009175; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd17503; MFS_LmrB_MDR_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR Gene3D; 1.20.1720.10; Multidrug resistance protein D; 1.
DR InterPro; IPR004638; EmrB-like.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR NCBIfam; TIGR00711; efflux_EmrB; 1.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF51; PERMEASE-RELATED; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009175};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 115..137
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..430
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 497..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 24..520
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 529 AA; 57641 MW; 2630742254517157 CRC64;
MSASIALPQT DVDYGVGSRR AWIAVMGGLI GAFMAILDIQ ITNASMKEIQ GSLGATLEEG
SWISTAYLVA EMIAIPLSGW LSTGLSVRRY LLWSTTAFIL SSLLCSMAWD LNSLIAFRAL
QGFFGGALIP LAFRLIVECL PFEKRAMGMA LFGVTATFAP SIGPTLGGWL TEHFSWHFLF
YINVPPGLLV LWMLAYGLQK GPIDWGKLGK VSWVGIATMA LGLGCLEVVL EEGNRKDWLG
SDVIRDLAII AAINLVLFVY LQLRSRNPLV NLRLLAHRDF ALSSLSYFLL GLGLFGAIYL
IPLYLSQIHN YSALEIGKVI MWMGFPQLLV LPLVPKLTQK LDPRYLAAWG FLLFALSYYL
NAHMTAQYAG EQMILAQIVR ALGQPFVLVP IGMIATMHLR QEDTPSASTL LNLIRNLGGA
CGIALVATML DNRFRQHLAY LKESLPAVSQ QAHTFLQQQA SSLFAAGADP MAADSMARKM
LSDTLVREAY MQAYNDVFFA IGGLLLVAVV AVLLIRPSSQ AGNSGAAGH
//
