ID A1SC76_NOCSJ Unreviewed; 539 AA.
AC A1SC76;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=FAD-dependent pyridine nucleotide-disulphide oxidoreductase {ECO:0000313|EMBL:ABL79411.1};
GN OrderedLocusNames=Noca_4827 {ECO:0000313|EMBL:ABL79411.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OG Plasmid pNOCA01 {ECO:0000313|EMBL:ABL79411.1,
OG ECO:0000313|Proteomes:UP000000640}.
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL79411.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RC PLASMID=pNOCA01 {ECO:0000313|Proteomes:UP000000640};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of plasmid pNOCA01 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL79411.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RC PLASMID=pNOCA01 {ECO:0000313|EMBL:ABL79411.1,
RC ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; CP000508; ABL79411.1; -; Genomic_DNA.
DR AlphaFoldDB; A1SC76; -.
DR KEGG; nca:Noca_4827; -.
DR eggNOG; COG1249; Bacteria.
DR HOGENOM; CLU_520687_0_0_11; -.
DR BioCyc; MetaCyc:MONOMER-19824; -.
DR Proteomes; UP000000640; Plasmid pNOCA01.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 3.30.390.30; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR016156; FAD/NAD-linked_Rdtase_dimer_sf.
DR InterPro; IPR004099; Pyr_nucl-diS_OxRdtase_dimer.
DR PANTHER; PTHR43014; MERCURIC REDUCTASE; 1.
DR PANTHER; PTHR43014:SF2; MERCURIC REDUCTASE; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF02852; Pyr_redox_dim; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF55424; FAD/NAD-linked reductases, dimerisation (C-terminal) domain; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:ABL79411.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640}.
FT DOMAIN 59..384
FT /note="FAD/NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF07992"
FT DOMAIN 406..511
FT /note="Pyridine nucleotide-disulphide oxidoreductase
FT dimerisation"
FT /evidence="ECO:0000259|Pfam:PF02852"
SQ SEQUENCE 539 AA; 60169 MW; E7FDB85D0FD076FE CRC64;
MVARSLTLAA TRANDEERPM DLRNSVLSMA EWEDLIHRAE TGEVNEPLEN VDHDDTRPYD
AIFIGGGAGG RFGSAYLQAR GGRQLVIDKW PFLGGSCPHQ ACVPHHLFSE AAREMDYMRW
NAGTLWFPEF DDKRASIRDL VDLFKAGRNN PHAFMNWQSK EQLGMEYILN AEATVIDANT
VEVSGRRYTT RNIVLATGAR SYVPDGIPGL ELHGVFDFAS LIEELDYEPS RCVIIGGSKI
ALEYGSFYQA AGCQTTIVSR SPLMRTASLH HVDEDLRTYV VGNMRKRGME ILEGAEPIEV
IGNGKVTGVR VRLADGSEKT IDTDFVFMGT GERPHTKPFV DALGIEVDEK GFVQVDSRMR
TSVPGVYAIG DLIGSPMEMF KARKCGMTAA RNIMGDPYEF DFSEYPDFLH TTYEVTWVGL
SEEEARAEYG DIAVIQMPPK GIRDDELALP CAEGSMLYAF TRPELTGFQK AVYDGKTRRL
LGAHHVGFGA KDAFQYLDHL IRKGITVDEM GEMNELFLNP DHFIQLSRLR AGQQHLTDL
//
