ID A1SED7_NOCSJ Unreviewed; 459 AA.
AC A1SED7;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=Succinate semialdehyde dehydrogenase {ECO:0000313|EMBL:ABL80172.1};
DE EC=1.2.1.16 {ECO:0000313|EMBL:ABL80172.1};
GN OrderedLocusNames=Noca_0646 {ECO:0000313|EMBL:ABL80172.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL80172.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL80172.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CP000509; ABL80172.1; -; Genomic_DNA.
DR AlphaFoldDB; A1SED7; -.
DR STRING; 196162.Noca_0646; -.
DR KEGG; nca:Noca_0646; -.
DR eggNOG; COG1012; Bacteria.
DR HOGENOM; CLU_005391_5_3_11; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:UniProtKB-EC.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640}.
FT DOMAIN 3..452
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 232
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 459 AA; 48313 MW; 8379A9B51F5E8B3E CRC64;
MTTFGVEDPA SLEIIAQVPD QGPDEARVAV DRAAAAFADW SRTSPRHRSD VLRRAFDLMM
RDSEELTGLI TSENGKSLVD AAAEVGYAAE FFRWFSEEAV RPSGEYGEAP TGGVRTIVTH
RPVGVAALVT PWNFPAAMVT RKIAPALAAG CTVVLKPAAE TPLTALAVGR ILSEAGVPDG
AVEIVTTTDA PGVVTAWLSD DRVRKVSFTG STGVGRALLH QAADRVLNAS MELGGNAPVV
VTDDADLGAA VAGTMIAKFR NSGQACTAAN RIFVHNDVAF DFVARLGAAV EKLSVGPAID
GAAIGPLITQ AALQRVTEAV DFAVREGARI SHQAQLPEAP GYFFPPTVLA GLAPDATILR
EEIFGPVAPV VVWHDEDELL ELVNDTEYGL AAYVFAGDIG RAVRLGERID AGMVGINRGL
VSDPSAPFGG VKQSGLGREG AREGLREFQE TQYLSVDWS
//
