ID A1SHM2_NOCSJ Unreviewed; 450 AA.
AC A1SHM2;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE SubName: Full=Crotonyl-CoA reductase {ECO:0000313|EMBL:ABL81307.1};
GN OrderedLocusNames=Noca_1795 {ECO:0000313|EMBL:ABL81307.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL81307.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL81307.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
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DR EMBL; CP000509; ABL81307.1; -; Genomic_DNA.
DR AlphaFoldDB; A1SHM2; -.
DR STRING; 196162.Noca_1795; -.
DR KEGG; nca:Noca_1795; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_5_0_11; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0043880; F:crotonyl-CoA reductase activity; IEA:InterPro.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 2.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR010085; Crot_CoA_red.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR01751; crot-CoA-red; 1.
DR PANTHER; PTHR44154; QUINONE OXIDOREDUCTASE; 1.
DR PANTHER; PTHR44154:SF1; QUINONE OXIDOREDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000640}.
FT DOMAIN 54..420
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 450 AA; 49831 MW; 97921EFE14D3C43F CRC64;
MQHILDAIMA ASDDPRSATE ADFAGLDLPE SYRAVTVHKD EVDMFDGLAT KEKDPRKSLH
VEDVPLPELG PGEAYVAVMA SAINYNTVWT SIFEPASTFG FLERYGRLSP LAKRHDLPYH
VVGSDLAGVV LATGPGVHLW KPGTEVVAHC LSVELEHPDG HSDTMLDPEQ RIWGFETNFG
GLAQIALVKA NQLMPKPAHL TWEEAASPGL VNCTAYRQLV SKNGGDMKQG DNVLIWGASG
GLGGFATQYA LNGGANPICV VSSEEKAEIC RKMGAELIIN RNEEGYRFWK DEQTQDPREW
KRFGSKIREL TGGEDIDIVF EHPGRETFGA SVYVTRKGGT ITTCASTSGY MHEYDNRYLW
MSLKKIISSH FANYRESWEA NRLIAKGKIH PTLSKTYALD DVGQATLDVH QNLHQGKVGV
LCLAPEEGLG VRDHEMRARH LEEINRFRDL
//
