ID A1SMM3_NOCSJ Unreviewed; 490 AA.
AC A1SMM3;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=Endoglycoceramidase {ECO:0000313|EMBL:ABL83058.1};
DE EC=3.2.1.123 {ECO:0000313|EMBL:ABL83058.1};
GN OrderedLocusNames=Noca_3558 {ECO:0000313|EMBL:ABL83058.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL83058.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL83058.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000509; ABL83058.1; -; Genomic_DNA.
DR RefSeq; WP_011756991.1; NC_008699.1.
DR AlphaFoldDB; A1SMM3; -.
DR STRING; 196162.Noca_3558; -.
DR CAZy; GH5; Glycoside Hydrolase Family 5.
DR KEGG; nca:Noca_3558; -.
DR eggNOG; COG2730; Bacteria.
DR HOGENOM; CLU_027657_1_0_11; -.
DR OrthoDB; 4771662at2; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0047876; F:endoglycosylceramidase activity; IEA:UniProtKB-EC.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF3; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361153};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..490
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002637287"
FT DOMAIN 71..360
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 400..480
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
SQ SEQUENCE 490 AA; 52941 MW; 3512F8852577A8EC CRC64;
MRLLAVLVTL GLLLLGPVPT ASASSDGATR ARTSGRWIVD PQGRVLVLHG LNMVSKIAPY
APDQVGFGRD DARFLARQGF TTVRLGLIWK AVEPEPGEYD DAYLARIEHT TEVLAAEGIW
TLLDFHQDLY NERFQGEGAP DWAVQDEGLP AQPQLGFPYN YFGMAPLLRA FYHFWANDPG
PGGVGLQDRY AAAWAHVAEY FADAPRVLGL DLFNEPWPGS AWSTCANPAG CPAFDAQLQA
FSQRAADAIR AVDRRTAVFY EPNVLFNNGA QTHVAPTGDR LGFSFHDYCL TAEADAEGAG
QQACGTFDDL VFQNAVQHGT DLGHPPLLTE FGATTDRTTL TTMVDRAAAH RVGWQYWAYC
GCDDPTTTGP GATQALVLDP SRPPVGDNVD RQKLRAIVVP YPLAVSGVPT AYSFDRDSRA
FEATWRTARA GGGGFAAGSR TTLSLPRLVY PDGYRVTVTG GRVVSAPDAR VLVVAQDRGA
SAVRLVVRGR
//
