ID A1SPW5_NOCSJ Unreviewed; 247 AA.
AC A1SPW5;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 70.
DE SubName: Full=Conserved membrane protein (DedA family) {ECO:0000313|EMBL:ABL83850.1};
GN OrderedLocusNames=Noca_4353 {ECO:0000313|EMBL:ABL83850.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL83850.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL83850.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU367016};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU367016}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the DedA family. {ECO:0000256|ARBA:ARBA00010792,
CC ECO:0000256|RuleBase:RU367016}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000509; ABL83850.1; -; Genomic_DNA.
DR AlphaFoldDB; A1SPW5; -.
DR STRING; 196162.Noca_4353; -.
DR KEGG; nca:Noca_4353; -.
DR eggNOG; COG0586; Bacteria.
DR HOGENOM; CLU_044208_6_0_11; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR032818; DedA.
DR InterPro; IPR032816; VTT_dom.
DR PANTHER; PTHR30353; INNER MEMBRANE PROTEIN DEDA-RELATED; 1.
DR PANTHER; PTHR30353:SF0; TRANSMEMBRANE PROTEIN; 1.
DR Pfam; PF09335; SNARE_assoc; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU367016};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU367016};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU367016};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU367016}.
FT TRANSMEM 30..63
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 75..97
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 162..186
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT TRANSMEM 198..215
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU367016"
FT DOMAIN 49..181
FT /note="VTT"
FT /evidence="ECO:0000259|Pfam:PF09335"
FT REGION 222..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 27775 MW; 248A3D512CC205C5 CRC64;
MMSVLPGQSM LLGMDWMDPN WLLDQFGVEF YWISLLIIFV ECGLFFPFLP GDTLLFALGL
FLNAERIDMF PGGPVVELVI AAVLLSAAAF LGNVAGYEIG RAIGPPLYHR EGRLLKKKYF
DQTHAFFERH GNKALVIGRF VPFVRTFITV VAGVTRMERR RFFLWSAVGA VLWVLSILML
GFTLGGVFPT LGENIDKTLI AILAFTVVPI AYEWWRHRRT ASRRGDDRDG DGVPDLDITG
VDATRRD
//
