ID A1TC62_MYCVP Unreviewed; 425 AA.
AC A1TC62;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 98.
DE SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:ABM14762.1};
GN OrderedLocusNames=Mvan_3985 {ECO:0000313|EMBL:ABM14762.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM14762.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM14762.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000511; ABM14762.1; -; Genomic_DNA.
DR AlphaFoldDB; A1TC62; -.
DR STRING; 350058.Mvan_3985; -.
DR KEGG; mva:Mvan_3985; -.
DR eggNOG; COG1309; Bacteria.
DR HOGENOM; CLU_055812_0_0_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR041490; KstR2_TetR_C.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF17932; TetR_C_24; 1.
DR Pfam; PF00440; TetR_N; 2.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 2.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 2.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00335}; Reference proteome {ECO:0000313|Proteomes:UP000009159};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 42..102
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DOMAIN 238..298
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 65..84
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT DNA_BIND 261..280
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 18..41
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 425 AA; 45664 MW; D239253766089432 CRC64;
MATRIRGDRA IGCRVSRSHG AAEEGAEGVT SVARPERGTR PSNRRELIGA AATELFCTRG
YEHVGMGDIA EAVAVGPSAL YRHFAGKQEL LDFVVAGCLG SATALVDSVD LEDFDLSLLR
AAEVSVSNRY TGILLGREAR HLAAGAQARL RVAVRHLIGR IAALLAVLRP DLDKDAADLM
AWSVVGIVLS PAFSQSDLSD REQARLLAQL IGGILTAEAP VGYTIERRRR ERTGLLPRSR
REALLQEAIR LFAERRYASV GIEDVAASLG MAGPSVYNHF DTKMDLLVTA LNRGAAYLYM
QASDGLAASD SAQDALSGLV ASYVEFALTH PALVDLLVTE VRNLPEPHRD AALTAQRDYV
EEWVHLLRQC HPDRARSAAR LQVQAVLSLV NLVARVPHLQ ATRATAGAVA EMGRHLLAVP
PASSA
//
