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Database: UniProt
Entry: A1TWF2_ACIAC
LinkDB: A1TWF2_ACIAC
Original site: A1TWF2_ACIAC 
ID   A1TWF2_ACIAC            Unreviewed;       770 AA.
AC   A1TWF2;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   28-MAR-2018, entry version 78.
DE   SubName: Full=Malate dehydrogenase (Oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase {ECO:0000313|EMBL:ABM35290.1};
DE            EC=1.1.1.40 {ECO:0000313|EMBL:ABM35290.1};
DE            EC=2.3.1.8 {ECO:0000313|EMBL:ABM35290.1};
GN   OrderedLocusNames=Aave_4759 {ECO:0000313|EMBL:ABM35290.1};
OS   Acidovorax citrulli (strain AAC00-1) (Acidovorax avenae subsp.
OS   citrulli).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Acidovorax.
OX   NCBI_TaxID=397945 {ECO:0000313|EMBL:ABM35290.1, ECO:0000313|Proteomes:UP000002596};
RN   [1] {ECO:0000313|EMBL:ABM35290.1, ECO:0000313|Proteomes:UP000002596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAC00-1 {ECO:0000313|EMBL:ABM35290.1,
RC   ECO:0000313|Proteomes:UP000002596};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H.,
RA   Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Stahl D.,
RA   Richardson P.;
RT   "Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000002596}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AAC00-1 {ECO:0000313|Proteomes:UP000002596};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Kiss H.,
RA   Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Stahl D.,
RA   Richardson P.;
RT   "Complete sequence of Acidovorax avenae subsp. citrulli AAC00-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP000512; ABM35290.1; -; Genomic_DNA.
DR   RefSeq; WP_011797756.1; NC_008752.1.
DR   ProteinModelPortal; A1TWF2; -.
DR   STRING; 397945.Aave_4759; -.
DR   EnsemblBacteria; ABM35290; ABM35290; Aave_4759.
DR   KEGG; aav:Aave_4759; -.
DR   eggNOG; ENOG4105C6K; Bacteria.
DR   eggNOG; COG0280; LUCA.
DR   eggNOG; COG0281; LUCA.
DR   HOGENOM; HOG000132448; -.
DR   KO; K00029; -.
DR   OMA; VYACMNG; -.
DR   OrthoDB; POG091H02AU; -.
DR   BioCyc; ACIT397945:G1G7T-4853-MONOMER; -.
DR   Proteomes; UP000002596; Chromosome.
DR   GO; GO:0004471; F:malate dehydrogenase (decarboxylating) (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004473; F:malate dehydrogenase (decarboxylating) (NADP+) activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0008948; F:oxaloacetate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008959; F:phosphate acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006108; P:malate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.10380; -; 1.
DR   InterPro; IPR032683; Malate_DH.
DR   InterPro; IPR012301; Malic_N_dom.
DR   InterPro; IPR037062; Malic_N_dom_sf.
DR   InterPro; IPR012302; Malic_NAD-bd.
DR   InterPro; IPR012188; ME_PTA.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002505; PTA_PTB.
DR   Pfam; PF12434; Malate_DH; 1.
DR   Pfam; PF00390; malic; 1.
DR   Pfam; PF03949; Malic_M; 1.
DR   Pfam; PF01515; PTA_PTB; 1.
DR   PIRSF; PIRSF036684; ME_PTA; 1.
DR   SMART; SM01274; malic; 1.
DR   SMART; SM00919; Malic_M; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000313|EMBL:ABM35290.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002596};
KW   Oxidoreductase {ECO:0000313|EMBL:ABM35290.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002596};
KW   Transferase {ECO:0000313|EMBL:ABM35290.1}.
FT   DOMAIN       30    163       malic. {ECO:0000259|SMART:SM01274}.
FT   DOMAIN      175    412       Malic_M. {ECO:0000259|SMART:SM00919}.
SQ   SEQUENCE   770 AA;  83023 MW;  DDD29392251D8209 CRC64;
     MSDTPPVNTT PDKRALLRQA ALEYHEFPKP GKIAIAATKQ MVNQHDLALA YSPGVAAPCE
     EIVKDPAAAF RYTSRGNLVG VISNGTAVLG LGDIGALASK PVMEGKAVLF KKFAGVDVFD
     IEINEKDPAK LVEVIAALEP TFGAINLEDI KAPDCFYVER ELRKRLNIPV FHDDQHGTAI
     TVAAAMLNAL KVVGKDIGEV RLVTSGAGAA ALACLNLLLK VGLKRENVFV TDLAGVVYEG
     RTELMDEDKI QFAQKTDART LAEVIEGADV FLGLSAGGVL KPAMVAKMAA RPVIFALANP
     NPEITPEDAH AVRGDVVMAT GRTDYPNQVN NVLCFPYIFR GALDCGATTI TLEMEIAAVH
     AIAELAQAEQ SEVVAAAYVG EPLAFGPEYL IPKPFDPRLM IKIAPAVAQA AADSGVAQRP
     IADMDAYRDH LQTFVYASGT MMKPIVNAAK LAARKRVAYA EGEEERVLRA AQIVVDEKIA
     RPTLIGRPAI IAQRVEKFGL RLKEGVDYDV VNVENDHRYR DFWQTYHRMT ERKGITVPIA
     KIEMRRRLAL IASMLLHKGE VDGMICGTWG HTAHHLNYID QVIGKRAGVN TYACMNGLLL
     PDRQVFLVDT HVNYDPTAEQ LAEITVMAAE EMMRFGIKPK AALLSHSNFG SSTQPSAVKM
     RQTLELLRVQ APWLEVDGEM HGDVALDAAL RTQVMPHSTL AGSANLLVLP NIDAANISYN
     LLKTAAGGGI AIGPVLLGAS EPVHILTASA TVRRIVNMTA LTVADANAAR
//
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