ID A1UFH9_MYCSK Unreviewed; 535 AA.
AC A1UFH9;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABL91587.1};
GN OrderedLocusNames=Mkms_2389 {ECO:0000313|EMBL:ABL91587.1};
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=189918 {ECO:0000313|EMBL:ABL91587.1};
RN [1] {ECO:0000313|EMBL:ABL91587.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:ABL91587.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000518; ABL91587.1; -; Genomic_DNA.
DR AlphaFoldDB; A1UFH9; -.
DR STRING; 189918.Mkms_2389; -.
DR KEGG; mkm:Mkms_2389; -.
DR HOGENOM; CLU_000022_23_7_11; -.
DR OrthoDB; 3671040at2; -.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR22754:SF32; DISCO-INTERACTING PROTEIN 2; 1.
DR PANTHER; PTHR22754; DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABL91587.1}.
FT DOMAIN 27..392
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 438..516
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 535 AA; 55542 MW; 7E5EEF285CB7ACD1 CRC64;
MTLRTNPLAS ALSDSMAAAD TDLVLLDRES GAWRRHPWSE VLARSMNVAE RIGDADASAV
GVIGEPNVEF VAAIVGSFLA GRGVSVLPGP VRGAAADQWA HNTLARFAGA GVSHVLTHGS
HLGHLRVADG SAAVHDVTTW AGPNRSAPLD ASLPTGDVAI LQGTAGSTGT PRTVRLSPDA
VLANLTGLSA RIGLERGHDV GCSWLPLYHD MGLSFLLTGA LAGVETWQAP TSAFQASPFR
WLNWLSDSRA TITAAPNMAF GMIGKYARRV TDVDLSNVRF ALNGGEPVDC ELTALFATAM
SRFGFSAGAL APSYGLAEST CAVTVPEPGD GLRTDEVAVG TDDGVSLRRH AVLGHAIPGM
QVRISPREGD ADVSGREVGE VEIRGSSMMS GYVGGASLDA QTWFATGDLG YLVDGALVVC
GRAKELITVA GRNIFPAEIE RVAAQVPGVR EGAVVAVGTG EGSIRPGLVI AAEFRGRDEA
GARSELVQQV ASQCGVVPSD VVFVRPGSLP RTSSGKLRRL AVKHSLEAGT EPQPR
//
