ID A1UI67_MYCSK Unreviewed; 359 AA.
AC A1UI67;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 95.
DE SubName: Full=Geranylgeranyl-diphosphate synthase {ECO:0000313|EMBL:ABL92525.1};
DE EC=2.5.1.29 {ECO:0000313|EMBL:ABL92525.1};
GN OrderedLocusNames=Mkms_3331 {ECO:0000313|EMBL:ABL92525.1};
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=189918 {ECO:0000313|EMBL:ABL92525.1};
RN [1] {ECO:0000313|EMBL:ABL92525.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:ABL92525.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000518; ABL92525.1; -; Genomic_DNA.
DR AlphaFoldDB; A1UI67; -.
DR STRING; 189918.Mkms_3331; -.
DR KEGG; mkm:Mkms_3331; -.
DR HOGENOM; CLU_014015_2_1_11; -.
DR OrthoDB; 4497239at2; -.
DR GO; GO:0004311; F:farnesyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466, ECO:0000313|EMBL:ABL92525.1}.
SQ SEQUENCE 359 AA; 38162 MW; 0E220C675146EA8B CRC64;
MDAAAPSAAE LAGAVTEQLR DYLSARRRDA AYIGSDYAEL TAALEEFVLR GGKRLRPAFA
YWGWRAVADR PADSGVLLLF SALELLHACA LVHDDVIDAS ATRRGLPTVH RLFADRHADR
GWHGSSEQFG LSAAILAGDL SLVWADDIVA SVDLPLDAHR RVQRVWADIR TEVLGGQFLD
IAAEASGAQT VASAMTVNTY KTASYTVSRP LQLGAAAAAD RPEVLEIFHQ LGTDIGVAFQ
LRDDVLGVFG DPAVTGKPSG DDLRSGKRTV LLAEAVELAE KTDQGTAALL RSSIGTDLSE
SQVRELCSAI ESVGALTAVE ERIALLTRRS LEALDAAPID PQAKAGLTEL ARLAANRSA
//
