ID A1UNE3_MYCSK Unreviewed; 374 AA.
AC A1UNE3;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Polyprenyl synthetase {ECO:0000313|EMBL:ABL94351.1};
GN OrderedLocusNames=Mkms_5162 {ECO:0000313|EMBL:ABL94351.1};
OS Mycobacterium sp. (strain KMS).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=189918 {ECO:0000313|EMBL:ABL94351.1};
RN [1] {ECO:0000313|EMBL:ABL94351.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KMS {ECO:0000313|EMBL:ABL94351.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Miller C.D.,
RA Richardson P.;
RT "Complete sequence of chromosome of Mycobacterium sp. KMS.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Isoprenoid biosynthesis. {ECO:0000256|ARBA:ARBA00005128}.
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|ARBA:ARBA00006706, ECO:0000256|RuleBase:RU004466}.
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DR EMBL; CP000518; ABL94351.1; -; Genomic_DNA.
DR AlphaFoldDB; A1UNE3; -.
DR STRING; 189918.Mkms_5162; -.
DR KEGG; mkm:Mkms_5162; -.
DR HOGENOM; CLU_014015_2_1_11; -.
DR OrthoDB; 4497239at2; -.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR12001:SF88; (2E,6E)-FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR12001; GERANYLGERANYL PYROPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 374 AA; 40402 MW; C71B90BFEC5AC4E2 CRC64;
MSGVDDRLLA AALRPAPARL TADSFDTWRR DVRRAAIDAV TEFVTDRCAD DLRLTGVDVT
LDVLSDFVSD GKCLRSTFAY LGWLAGAAPD DAALRAAASF DLLHVFALLQ DDVMDDSPLR
RGRPAAHVRF AQWHRDNGLN GSAERFGASA AVLLGDLCLV WAGQMMRESG LGDRALARAW
PRYDAMRTEL AVGQFADLVN DAGGRPTLED VLDVARRKSG NYTVRRPLEI GGALAGCPDA
TLGLLGRYGA AVGEAFQLRD DLLGIFGAPT VTGKPAGGDL SEHKATSVVV AAHRLAEPSV
RNQLTELMSR RDLDAGDITR WQHLIAATGA VQWIEQLIDR RLSHALERIH TSPLDDTVRT
ALVNMAAVCT RRAA
//
