ID A1WRJ7_VEREI Unreviewed; 356 AA.
AC A1WRJ7;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=Cobalamin synthesis protein, P47K {ECO:0000313|EMBL:ABM60254.1};
GN OrderedLocusNames=Veis_4556 {ECO:0000313|EMBL:ABM60254.1};
OS Verminephrobacter eiseniae (strain EF01-2).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Verminephrobacter.
OX NCBI_TaxID=391735 {ECO:0000313|EMBL:ABM60254.1, ECO:0000313|Proteomes:UP000000374};
RN [1] {ECO:0000313|Proteomes:UP000000374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EF01-2 {ECO:0000313|Proteomes:UP000000374};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
RT "Complete sequence of chromosome 1 of Verminephrobacter eiseniae EF01-2.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; CP000542; ABM60254.1; -; Genomic_DNA.
DR RefSeq; WP_011812238.1; NC_008786.1.
DR AlphaFoldDB; A1WRJ7; -.
DR STRING; 391735.Veis_4556; -.
DR GeneID; 76462849; -.
DR KEGG; vei:Veis_4556; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_0_0_4; -.
DR OrthoDB; 9808822at2; -.
DR Proteomes; UP000000374; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000000374}.
FT DOMAIN 261..355
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 217..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 356 AA; 39639 MW; 28CF8530A64A930D CRC64;
MSLIPVTILT GFLGSGKTTL LKRLLSEAHG QKIAVIENEF GAENIDTDIL VTESKEQIVQ
MNNGCICCTI REDLRATLQL LASKKRQGLL DFERIVIETT GLADPGPVAQ TFFMDDEVAQ
SCLIDAIITL VDAKHATGQL NDRQEARRQV GFADQIFLSK TDLVSAEETR ALIQRLKHMN
PRAPIQAVHF GAVPIGQVLD LRGFNLHAKL DIDPDFLSEQ DAHGHGHEHE HEHHEHAHGA
HCDHPSHQHG GPGHHHHDDD VKSFVFRSER PFDPARLEDF LGAMVNVYGP RMLRYKGVLQ
MKGTDRKVIF QGVHQLMGSD LGPQWADGEA RTSKMVFIGI DLPRDIFLQG LEQSLV
//
