ID   A1X1V4_CARRO            Unreviewed;       628 AA.
AC   A1X1V4;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Hemocyanin subunit IIIb {ECO:0000313|EMBL:AAZ40338.1};
OS   Carcinoscorpius rotundicauda (Mangrove horseshoe crab) (Limulus
OS   rotundicauda).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Merostomata;
OC   Xiphosura; Limulidae; Carcinoscorpius.
OX   NCBI_TaxID=6848 {ECO:0000313|EMBL:AAZ40338.1};
RN   [1] {ECO:0000313|EMBL:AAZ40338.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Jiang N., Tan N.S., Ho B., Ding J.L.;
RT   "Carcinoscorpius rotundicauda hemocyain subunit IIIb.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hemocyanins are copper-containing oxygen carriers occurring
CC       freely dissolved in the hemolymph of many mollusks and arthropods.
CC       {ECO:0000256|ARBA:ARBA00002958}.
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space
CC       {ECO:0000256|ARBA:ARBA00004239}.
CC   -!- SIMILARITY: Belongs to the tyrosinase family. Hemocyanin subfamily.
CC       {ECO:0000256|ARBA:ARBA00009470}.
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DR   EMBL; DQ090487; AAZ40338.1; -; mRNA.
DR   AlphaFoldDB; A1X1V4; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0005344; F:oxygen carrier activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR   Gene3D; 2.60.40.1520; Hemocyanin, C-terminal domain; 1.
DR   Gene3D; 1.20.1370.10; Hemocyanin, N-terminal domain; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR013788; Hemocyanin/hexamerin.
DR   InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR   InterPro; IPR005203; Hemocyanin_C.
DR   InterPro; IPR037020; Hemocyanin_C_sf.
DR   InterPro; IPR005204; Hemocyanin_N.
DR   InterPro; IPR036697; Hemocyanin_N_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR002227; Tyrosinase_Cu-bd.
DR   PANTHER; PTHR11511:SF5; FAT-BODY PROTEIN 1-RELATED; 1.
DR   PANTHER; PTHR11511; LARVAL STORAGE PROTEIN/PHENOLOXIDASE; 1.
DR   Pfam; PF03723; Hemocyanin_C; 1.
DR   Pfam; PF00372; Hemocyanin_M; 1.
DR   Pfam; PF03722; Hemocyanin_N; 1.
DR   PRINTS; PR00187; HAEMOCYANIN.
DR   SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR   SUPFAM; SSF81296; E set domains; 1.
DR   SUPFAM; SSF48050; Hemocyanin, N-terminal domain; 1.
DR   PROSITE; PS00209; HEMOCYANIN_1; 1.
DR   PROSITE; PS00210; HEMOCYANIN_2; 1.
DR   PROSITE; PS00498; TYROSINASE_2; 1.
PE   2: Evidence at transcript level;
KW   Copper {ECO:0000256|ARBA:ARBA00023008};
KW   Oxygen transport {ECO:0000256|ARBA:ARBA00022621};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          356..367
FT                   /note="Tyrosinase copper-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS00498"
SQ   SEQUENCE   628 AA;  72827 MW;  39F86295D626A358 CRC64;
     MTIQEKQNKI LSLLEHLNNL TKHQLPVDER DPRLKDVGHL LRGGLFSLFH MEHLTEATHL
     YETLYNAEDF DDFIHLCEQA KDVVNEGMFA YAISVAVLHR NDCKGLALPP IQEIFPDRFI
     PAETITEAIK DDHNRHDHEV LTVEARDTGN ILNPEQHLAY FREDIETNAH HWHWHIVYPA
     TRNSKVMHKV KDRKGELFFY MHQQMCARYD CERLSVGLQR MLPFQNFEEE LEGYSAHLTS
     LVSGLHYASR PEGMHLHDLK GVVNLYEMER WRERIMDAIE RGLVFDDDNH EHKLEEPHGI
     DMLGAIIEAS HDSVKHDFYG SIHNWGHVMF ARLHDPDGRY HDNPGVMSDT ATSLRDPIFY
     RFHRYIDNMF QTYKATLHSH EHHQLTFSGV QIDNVTVKAK QPNVINTYTT ESELELSHGI
     HMKGPTKVKY HHLDHDKFDY SISVNNTSGL AKNATFRIFL GPKYDELGNL LTPEQQRRFF
     IELDKFHREV PTGKSVITRS SADSSVTISH VPTFEELRNG KGVDVNNSEF CSCGWPQHML
     IPRGNYLGME FQLFVMLTDW EQDKAGKDLE HLTCADAVSY CGARDHLYPD KKPMGYPFDR
     PIKAHTVEEF LTPNMSLTDV KIQYKGNI
//