ID ZN394_PANPA Reviewed; 561 AA.
AC A1YG48;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 03-APR-2013, entry version 31.
DE RecName: Full=Zinc finger protein 394;
GN Name=ZNF394;
OS Pan paniscus (Pygmy chimpanzee) (Bonobo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC Catarrhini; Hominidae; Pan.
OX NCBI_TaxID=9597;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA Nickel G.C., Tefft D.L., Trevarthen K., Funt J., Adams M.D.;
RT "Positive selection in transcription factor genes on the human
RT lineage.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus (Potential).
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family.
CC -!- SIMILARITY: Contains 7 C2H2-type zinc fingers.
CC -!- SIMILARITY: Contains 1 KRAB domain.
CC -!- SIMILARITY: Contains 1 SCAN box domain.
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DR EMBL; DQ977217; ABM54273.1; -; Genomic_DNA.
DR ProteinModelPortal; A1YG48; -.
DR SMR; A1YG48; 58-145, 356-548.
DR HOVERGEN; HBG018163; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
DR GO; GO:0016032; P:viral reproduction; IEA:InterPro.
DR Gene3D; 3.30.160.60; -; 7.
DR InterPro; IPR001909; Krueppel-associated_box.
DR InterPro; IPR008916; Retrov_capsid_C.
DR InterPro; IPR003309; Tscrpt_reg_SCAN.
DR InterPro; IPR007087; Znf_C2H2.
DR InterPro; IPR015880; Znf_C2H2-like.
DR InterPro; IPR013087; Znf_C2H2/integrase_DNA-bd.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF02023; SCAN; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00431; SCAN; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF109640; Krueppel-associated_box; 1.
DR SUPFAM; SSF47353; Retrov_capsid_C; 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS50804; SCAN_BOX; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1 561 Zinc finger protein 394.
FT /FTId=PRO_0000285473.
FT DOMAIN 64 146 SCAN box.
FT DOMAIN 155 230 KRAB.
FT ZN_FING 358 380 C2H2-type 1.
FT ZN_FING 386 408 C2H2-type 2.
FT ZN_FING 414 436 C2H2-type 3.
FT ZN_FING 442 463 C2H2-type 4.
FT ZN_FING 469 491 C2H2-type 5.
FT ZN_FING 497 519 C2H2-type 6.
FT ZN_FING 525 547 C2H2-type 7.
SQ SEQUENCE 561 AA; 64278 MW; BB7B8CB00E1BA023 CRC64;
MNSSLTAQRR GSDAELGPWV MAARSKDAAP SQRDGLLPVK VEEDSLGSWE PSYPAASPDP
ETSRLHFRQL RYQEVAGPEE ALSRLRELCR RWLRPELLSK EQILELLVLE QFLTILPEEL
QAWVREHCPE SGEEAVAVVR ALQRALDGTS SQGMVTFEDM AVSLTWEEWE RLDPARSDFC
RESAQKDSGS TVPPSLESRV ENKELIPVQQ ILEEAEPQGR LQEAFQGKRP LFSKCVSTHE
DRVEKQSGDP LPLKLENSPE AEGFNSISDV NKNGSIEGED SKNNELQNSA RCSNLVLCQH
IPKAERPTDS EEHGNKCKQS FHMVTWHVLK PHKSDSGDSF HHSSLFETQR QLHEERPYKC
GNCGKSFKQR SDLFRHQRIH TGEKPYGCQE CGKSFSQSAA LTKHQRTHTG EKPYTCLKCG
ERFRQNSHLN RHQSTHSRDK HFKCEECGET CHISNLFRHQ RLHKGERPYK CEECEKSFKQ
RSDLFKHHRI HTGEKPYGCS VCGKRFNQSA TLIKHQRIHT GEKPYKCLEC GERFRQSTHL
IRHQRIHQNK VLSAGRGGSR L
//
