ID   A1YGV3_ENTFL            Unreviewed;       197 AA.
AC   A1YGV3;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   28-JUN-2023, entry version 41.
DE   RecName: Full=Serine protease {ECO:0000256|RuleBase:RU004296};
DE            EC=3.4.21.- {ECO:0000256|RuleBase:RU004296};
GN   Name=sprE {ECO:0000313|EMBL:ABL96460.1};
OS   Enterococcus faecalis (Streptococcus faecalis).
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=1351 {ECO:0000313|EMBL:ABL96460.1};
RN   [1] {ECO:0000313|EMBL:ABL96460.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=NIPH 163/01 {ECO:0000313|EMBL:ABL96460.1};
RA   Kawalec M., Jakubczak A.;
RT   "The polymorphism of sprE coding for extracellular serine proteinase of
RT   Enterococcus faecalis - convergent evolution and possible horizontal
RT   transfer of the pathogenicity factor gene.";
RL   Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S1B family.
CC       {ECO:0000256|ARBA:ARBA00008764, ECO:0000256|RuleBase:RU004296}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DQ985684; ABL96460.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1YGV3; -.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; Trypsin-like serine proteases; 2.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR008256; Peptidase_S1B.
DR   InterPro; IPR028301; V8_his_AS.
DR   Pfam; PF13365; Trypsin_2; 1.
DR   PRINTS; PR00839; V8PROTEASE.
DR   SUPFAM; SSF50494; Trypsin-like serine proteases; 1.
DR   PROSITE; PS00672; V8_HIS; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|RuleBase:RU004296};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU004296};
KW   Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW   ECO:0000256|RuleBase:RU004296}; Signal {ECO:0000256|ARBA:ARBA00022729}.
SQ   SEQUENCE   197 AA;  21384 MW;  300AF7DC484D42EC CRC64;
     MKKFSIRKIS AGFLFLILVT LIAGFSLSAN AEEYIVPAES HSRQKRSLLD PEDRRQEVAD
     TTEAPFASIG RIISPASKPG YISLGTGFVV GTNTIVTNNH VAESFKNAKV LNPNAKDDAW
     FYPGRDGSAT PFGKFKVIDV AFSPNADIAV VTVGKQNDRP DGPELGEILT PFVLKKFESS
     DTHVTISGYP GEKNHTQ
//