ID A1Z2P5_ICTPU Unreviewed; 227 AA.
AC A1Z2P5;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=B-cell antigen receptor complex-associated protein alpha chain {ECO:0000313|EMBL:AHH37227.1, ECO:0000313|RefSeq:NP_001187165.1};
DE SubName: Full=CD79a {ECO:0000313|EMBL:ABM53182.1};
GN Name=Cd79a {ECO:0000313|EMBL:AHH37227.1};
GN Synonyms=cd79a {ECO:0000313|RefSeq:NP_001187165.1};
OS Ictalurus punctatus (Channel catfish) (Silurus punctatus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Siluriformes;
OC Ictaluridae; Ictalurus.
OX NCBI_TaxID=7998 {ECO:0000313|EMBL:ABM53182.1};
RN [1] {ECO:0000313|EMBL:ABM53182.1, ECO:0000313|RefSeq:NP_001187165.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18572245; DOI=10.1016/j.dci.2008.05.008;
RA Sahoo M., Edholm E.S., Stafford J.L., Bengten E., Miller N.W., Wilson M.;
RT "B cell receptor accessory molecules in the channel catfish, Ictalurus
RT punctatus.";
RL Dev. Comp. Immunol. 32:1385-1397(2008).
RN [2] {ECO:0000313|EMBL:AHH37227.1, ECO:0000313|RefSeq:NP_001187165.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Mixed {ECO:0000313|EMBL:AHH37227.1};
RX PubMed=23127152; DOI=10.1186/1471-2164-13-595;
RA Liu S., Zhang Y., Zhou Z., Waldbieser G., Sun F., Lu J., Zhang J.,
RA Jiang Y., Zhang H., Wang X., Rajendran K.V., Khoo L., Kucuktas H.,
RA Peatman E., Liu Z.;
RT "Efficient assembly and annotation of the transcriptome of catfish by RNA-
RT Seq analysis of a doubled haploid homozygote.";
RL BMC Genomics 13:595-595(2012).
RN [3] {ECO:0000313|RefSeq:NP_001187165.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; EF173897; ABM53182.1; -; mRNA.
DR EMBL; JT405548; AHH37227.1; -; mRNA.
DR RefSeq; NP_001187165.1; NM_001200236.1.
DR STRING; 7998.ENSIPUP00000028478; -.
DR Ensembl; ENSIPUT00000029640; ENSIPUP00000028478; ENSIPUG00000019281.
DR GeneID; 100304994; -.
DR KEGG; ipu:100304994; -.
DR CTD; 973; -.
DR OMA; ADLKCCY; -.
DR OrthoDB; 5361630at2759; -.
DR Proteomes; UP000221080; Chromosome 23.
DR GO; GO:0019815; C:B cell receptor complex; IEA:InterPro.
DR GO; GO:0050853; P:B cell receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR039695; CD79a/CD79b.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR PANTHER; PTHR14334; B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR14334:SF1; B-CELL ANTIGEN RECEPTOR COMPLEX-ASSOCIATED PROTEIN ALPHA CHAIN; 1.
DR SMART; SM00409; IG; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 2: Evidence at transcript level;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000313|EMBL:AHH37227.1, ECO:0000313|RefSeq:NP_001187165.1};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..227
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001187165.1"
FT /id="PRO_5011323884"
FT DOMAIN 22..121
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 227 AA; 25553 MW; 11FBB9088DB561A3 CRC64;
MEARFVFLFC FLAAAANAAT SPKIQLGFDV PSLRLAISQT ASMSCCYTGI VRVPSQWIRL
VMNSRNTTKR TSINETNARV KLDQGQRNKQ HCEILILKDI VLNDTGLYQC VLTESNNTVF
TPGTFLQVYV PVHMILNINE RSKNSIITAE GVLLLLLVLI PGTMLICKSK GLNNIEKRMG
REEENIYEGL NLDDCNSTYH QIQRSLVQGP YQDVINNDED DIQLEKP
//
