ID A2AE38_MOUSE Unreviewed; 206 AA.
AC A2AE38;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-JAN-2016, sequence version 2.
DT 27-MAR-2024, entry version 122.
DE SubName: Full=Adhesion molecule with Ig like domain 1 {ECO:0000313|Ensembl:ENSMUSP00000102272.4};
DE Flags: Fragment;
GN Name=Amigo1 {ECO:0000313|Ensembl:ENSMUSP00000102272.4,
GN ECO:0000313|MGI:MGI:2653612};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000102272.4, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000102272.4, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102272.4,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [3] {ECO:0000313|Ensembl:ENSMUSP00000102272.4}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000102272.4};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR PeptideAtlas; A2AE38; -.
DR ProteomicsDB; 326172; -.
DR Antibodypedia; 53745; 359 antibodies from 34 providers.
DR Ensembl; ENSMUST00000106661.4; ENSMUSP00000102272.4; ENSMUSG00000050947.10.
DR AGR; MGI:2653612; -.
DR MGI; MGI:2653612; Amigo1.
DR VEuPathDB; HostDB:ENSMUSG00000050947; -.
DR GeneTree; ENSGT00950000183146; -.
DR HOGENOM; CLU_1450851_0_0_1; -.
DR Proteomes; UP000000589; Chromosome 3.
DR Bgee; ENSMUSG00000050947; Expressed in dentate gyrus of hippocampal formation granule cell and 147 other cell types or tissues.
DR ExpressionAtlas; A2AE38; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 1: Evidence at protein level;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Proteomics identification {ECO:0007829|ProteomicsDB:A2AE38};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..67
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 125..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000102272.4"
SQ SEQUENCE 206 AA; 22359 MW; A7E49866C25DA579 CRC64;
XTIRCDTKQQ GMTKVWVSPS NEQVLSQGSN GSVSVRNGDL FFKKVQVEDG GVYTCYAMGE
TFNETLSVEL KVYNFTLHGH HDTLNTAYTT LVGCILSVVL VLIYLYLTPC RCWCRGVEKP
SSHQGDSLSS SMLSTTPNHD PMAGGDKDDG FDRRVAFLEP AGPGQGQNGK LKPGNTLPVP
EATGLFPPLC TPGWQTSEPM GSITRQ
//
