ID   A2D4Y7_ATEGE            Unreviewed;       580 AA.
AC   A2D4Y7;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   22-FEB-2023, entry version 60.
DE   SubName: Full=SLC26A10 {ECO:0000313|EMBL:ABM65984.1};
GN   Name=SLC26A10 {ECO:0000313|EMBL:ABM65984.1};
OS   Ateles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Atelidae;
OC   Atelinae; Ateles.
OX   NCBI_TaxID=9509 {ECO:0000313|EMBL:ABM65984.1};
RN   [1] {ECO:0000313|EMBL:ABM65984.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=18689901; DOI=10.1534/genetics.108.090548;
RA   Nickel G.C., Tefft D.L., Goglin K., Adams M.D.;
RT   "An empirical test for branch-specific positive selection.";
RL   Genetics 179:2183-2193(2008).
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DR   EMBL; DQ976634; ABM65984.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2D4Y7; -.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   CDD; cd13241; PH2_Kalirin_Trio_p63RhoGEF; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR22826:SF117; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 4B-RELATED; 1.
DR   PANTHER; PTHR22826; RHO GUANINE EXCHANGE FACTOR-RELATED; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
FT   DOMAIN          160..336
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          48..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          128..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          483..524
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          543..569
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        48..64
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   580 AA;  63799 MW;  66C688B916163598 CRC64;
     MRGEHKGGRC ACPRVIRKVL AKCGCCFARG GRESYSIAGS EGSISASAAS GLAAPSGPSS
     GLSSGPCSPG PPGPVSGLRK WLDHSKHCLS VETEADSGQP GPYENWILEP ALATGEELPE
     LTLLTTLLEG PGDKTQPPEE ETLSQAPESE EEQKKKALER SMYVLSELVE TEKMYVDDLG
     QIVEGYMATM AAQGVPESLR GRDRIVFGNI QQIYEWHRDY FLQELRRCLK DPDWLAQLFI
     KHERRLHMYV VYCQNKPKSE HVVSEFGDSY FEELRQQLGH RLQLNDLLIK PVQRIMKYQL
     LLKDFLKYYS RAGMDTAELE QAVEVMCFVP KRCNDMMTLG RLRGFEGKLT AQGKLLGQDT
     FWVTEPEAGG LLSSRGRERR VFLFEQIVIF SEALGGGMRG GTQPGYVYKS SIKVSCLGLE
     GNLQGDPCRF ALTSRGPEGG IQRYVLQAAD PAVSQAWIKH VAQILESQRD FLNALQSPIE
     YQRRESQTNS LGRPGGLGVG SPGRIRLGDR AQGSAHTPIN GSLPSLLLSP KGEVARAPLP
     LDTQALGDIP QAPHDSLPVP PTPNTPPCQA RLAKLDEDEL
//