ID A2D553_ATEGE Unreviewed; 345 AA.
AC A2D553;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE SubName: Full=NOTCH2 {ECO:0000313|EMBL:ABM66050.1};
DE Flags: Fragment;
GN Name=NOTCH2 {ECO:0000313|EMBL:ABM66050.1};
OS Ateles geoffroyi (Black-handed spider monkey) (Geoffroy's spider monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Atelidae;
OC Atelinae; Ateles.
OX NCBI_TaxID=9509 {ECO:0000313|EMBL:ABM66050.1};
RN [1] {ECO:0000313|EMBL:ABM66050.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18689901; DOI=10.1534/genetics.108.090548;
RA Nickel G.C., Tefft D.L., Goglin K., Adams M.D.;
RT "An empirical test for branch-specific positive selection.";
RL Genetics 179:2183-2193(2008).
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DR EMBL; DQ976665; ABM66050.1; -; Genomic_DNA.
DR GO; GO:0043235; C:receptor complex; IEA:InterPro.
DR GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0071228; P:cellular response to tumor cell; IEA:InterPro.
DR GO; GO:0007219; P:Notch signaling pathway; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR InterPro; IPR022336; Notch_2.
DR InterPro; IPR024600; Notch_C.
DR PRINTS; PR01985; NOTCH2.
DR SMART; SM01334; DUF3454; 1.
PE 4: Predicted;
FT DOMAIN 254..319
FT /note="Notch C-terminal"
FT /evidence="ECO:0000259|SMART:SM01334"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 187..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..345
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 258..277
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABM66050.1"
SQ SEQUENCE 345 AA; 36286 MW; 5538E5C9364CBB17 CRC64;
KGSRRKKSLS EKVQLSESSV TLSPVDSLES PHTYVSDTTS SPMITSPGIL QASPNPMLAT
AAPPASVHAQ HALSFSNLHE MQPLAHGASP VLPSVSQLLS HHHIVPPGSG SAGSLGRLHP
VPVPADWMNR LEMNETQYNE MFGMVLAPAE GAHPGIAPQS RPPEGKHITT PREPLPPIVT
FQLIPKGSIA QPAGAPQPQS TCPPAVAGPL PTMYQIPEMA RLPSMAFPTA MXPQQDGQVA
QTILPAYHPF PASVGKYPTP PSQHSYASSN AAERTPSHSG HLQGEHPYLT PSPESPDQWS
SSSPHSASDW SDVTTSPTPG GAGGGQRGPG THMSEPPHNN MQVYA
//
