ID A2D5E7_HYLKL Unreviewed; 86 AA.
AC A2D5E7;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=NOTCH2 {ECO:0000313|EMBL:ABM67385.1};
DE Flags: Fragment;
GN Name=NOTCH2 {ECO:0000313|EMBL:ABM67385.1};
OS Hylobates klossii (Kloss's gibbon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae;
OC Hylobates.
OX NCBI_TaxID=9587 {ECO:0000313|EMBL:ABM67385.1};
RN [1] {ECO:0000313|EMBL:ABM67385.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=18689901; DOI=10.1534/genetics.108.090548;
RA Nickel G.C., Tefft D.L., Goglin K., Adams M.D.;
RT "An empirical test for branch-specific positive selection.";
RL Genetics 179:2183-2193(2008).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; DQ976710; ABM67385.1; -; Genomic_DNA.
DR AlphaFoldDB; A2D5E7; -.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR PANTHER; PTHR12916; CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2; 1.
DR PANTHER; PTHR12916:SF4; NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1-RELATED; 1.
DR Pfam; PF00008; EGF; 2.
DR PRINTS; PR00010; EGFBLOOD.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00179; EGF_CA; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 2.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}.
FT DOMAIN 1..15
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 17..53
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 55..86
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 5..14
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 43..52
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABM67385.1"
FT NON_TER 86
FT /evidence="ECO:0000313|EMBL:ABM67385.1"
SQ SEQUENCE 86 AA; 9411 MW; 50290872DE39B836 CRC64;
YKCLCDAGWV GINCEVDKNE CLSNPCQNGG TCDNLVNGYR CTCKKGFKGY NCQVNIDECA
SNPCLNQGTC FDDISGYTCH CVLPYT
//
