ID A2QPL6_ASPNC Unreviewed; 608 AA.
AC A2QPL6;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Contig An07c0370, genomic contig {ECO:0000313|EMBL:CAK39753.1};
DE EC=4.2.1.9 {ECO:0000313|EMBL:CAK39753.1};
GN ORFNames=An07g09870 {ECO:0000313|EMBL:CAK39753.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK39753.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK39753.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the IlvD/Edd family.
CC {ECO:0000256|ARBA:ARBA00006486}.
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DR EMBL; AM270154; CAK39753.1; -; Genomic_DNA.
DR RefSeq; XP_001392062.1; XM_001392025.1.
DR AlphaFoldDB; A2QPL6; -.
DR EnsemblFungi; CAK39753; CAK39753; An07g09870.
DR GeneID; 4982256; -.
DR KEGG; ang:An07g09870; -.
DR VEuPathDB; FungiDB:An07g09870; -.
DR HOGENOM; CLU_014271_3_0_1; -.
DR OrthoDB; 238at2759; -.
DR Proteomes; UP000006706; Chromosome 4L.
DR GO; GO:0004160; F:dihydroxy-acid dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0019752; P:carboxylic acid metabolic process; IEA:UniProt.
DR GO; GO:0044238; P:primary metabolic process; IEA:UniProt.
DR Gene3D; 3.50.30.80; IlvD/EDD C-terminal domain-like; 1.
DR InterPro; IPR042096; Dihydro-acid_dehy_C.
DR InterPro; IPR000581; DiOHA_6PGluconate_deHydtase.
DR InterPro; IPR020558; DiOHA_6PGluconate_deHydtase_CS.
DR InterPro; IPR037237; IlvD/EDD_N.
DR PANTHER; PTHR43183:SF1; HYPOTHETICAL DIHYDROXY-ACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43183; HYPOTHETICAL DIHYDROXYACID DEHYDRATASE (EUROFUNG)-RELATED; 1.
DR Pfam; PF00920; ILVD_EDD; 1.
DR SUPFAM; SSF143975; IlvD/EDD N-terminal domain-like; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
DR PROSITE; PS00886; ILVD_EDD_1; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:CAK39753.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
SQ SEQUENCE 608 AA; 64991 MW; 0800F941C1C69346 CRC64;
MESTSEPTSQ SDYDLSTPIN STSGLRQGLS SYGDAHFSLF LRKVFIKALG YSDEALSRPI
VGIINTYSGF NPCHANAPQL IEAVKRGVHL QGGLAIEFPT ISIQESFAYP TSMFLRNLMS
MDTEEMIRAQ PLDACVMIGG CDKTVPAQLM GGISANKPIL PLITGPMLPG SHRGQRIGAC
TDCRNNWAAF RAEEIDIEEI SAINEELAPT VGTCGVMGTA STMACVTAAL GMMPLRGASA
PAVSSARIRV AEETGANAVA VARAERRPQD ILSKESFLNA ITVLQAIGGS TNAVVHLMAI
VNRHPKLQGL ITLQTIEEVG QRTPLLIDLK PSGDNYMNDF HNAGGMLALL HTLRPLLHLS
AMTISGKTLG EVLDSTPFRT FPLSQQIIRP LSDPLHPSSS LVVLRGNIAP DGAVMKASAS
KDRRLLSHTG PAVVFENSAD LAKRIDDPNL EVTPDSVLVL KGIGPRGNPG MPEAGLIPIP
RKLGSAGVKD MLRLSDGRMS GTAGGTIVLH ISPESALRES PFGVVQTGDS ITCDITMRKL
QLEISDEELN RRIAVRKQTF EASGAEASHV QERKRGYRAL YERSVNQAQD GADFDFLSAN
GPSLNDGK
//
