ID A2QS25_ASPNC Unreviewed; 517 AA.
AC A2QS25;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE SubName: Full=Contig An08c0210, genomic contig {ECO:0000313|EMBL:CAK45697.1};
DE EC=1.14.13.8 {ECO:0000313|EMBL:CAK45697.1};
GN ORFNames=An08g08060 {ECO:0000313|EMBL:CAK45697.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK45697.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK45697.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the FMO family. {ECO:0000256|ARBA:ARBA00009183}.
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DR EMBL; AM270176; CAK45697.1; -; Genomic_DNA.
DR RefSeq; XP_001392921.1; XM_001392884.2.
DR AlphaFoldDB; A2QS25; -.
DR EnsemblFungi; CAK45697; CAK45697; An08g08060.
DR GeneID; 4983125; -.
DR KEGG; ang:An08g08060; -.
DR VEuPathDB; FungiDB:An08g08060; -.
DR HOGENOM; CLU_024886_0_0_1; -.
DR OrthoDB; 1826198at2759; -.
DR Proteomes; UP000006706; Chromosome 8R.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0047822; F:hypotaurine dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:UniProtKB-EC.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR23023; DIMETHYLANILINE MONOOXYGENASE; 1.
DR PANTHER; PTHR23023:SF62; FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_6G14280); 1.
DR Pfam; PF00743; FMO-like; 1.
DR PRINTS; PR00469; PNDRDTASEII.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAK45697.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 460..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 517 AA; 58443 MW; 946AD1195DAF41B9 CRC64;
MAESESVFSL SAFIRNPLLQ SFTICYMLFQ NLLNWIFAPN PPKPSSVANG VPKKRVAVIG
AGLTGVSAAA HCVGHGFDVE IFEARSKDKG LGGIWSRVNS TSSLQIHSIM YRFHPSVQYD
TAYPTQAEIK EQIVDLWKRY GLQKHTTFNT PVTSVKQTKN GRWIINNEED KYGRFDGIIA
SVGVCGDPKM PTMPDQDRFK GEIYHSSELD GRQVEGKRVL IVGGGASAIE ALEFAVKSKA
AEIDVLSRSD KWIIPRNVFV QSLLAMNILG QETSLSWIPE SLLRKFFYRD LSDIAPSGGL
FTQTPMANSE LFEQIRDGKA RWLRGDIVSL EEDGVRFNFR GNGVPKGGPG HEDLVPGDII
ILATGFKRPS LSFLPNDAFE EPYSPPSWYL QVFPPKYPSI CANNSTYVNA IGTVGNMHIG
IYTRFLLMFL TDPLSRPTEG RMRTWIDFTR FMKRLSPVGA FDFFTYTELL YWFVFCILVN
PFRWKWAPFV LFGVGWTLPL EVVKQEENFR KELRRQH
//
