ID A2R6Y4_ASPNC Unreviewed; 343 AA.
AC A2R6Y4;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 88.
DE SubName: Full=Contig An16c0060, genomic contig {ECO:0000313|EMBL:CAK42780.1};
DE EC=1.3.1.- {ECO:0000313|EMBL:CAK42780.1};
GN ORFNames=An16g01630 {ECO:0000313|EMBL:CAK42780.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK42780.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK42780.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; AM270358; CAK42780.1; -; Genomic_DNA.
DR RefSeq; XP_001397476.1; XM_001397439.2.
DR AlphaFoldDB; A2R6Y4; -.
DR EnsemblFungi; CAK42780; CAK42780; An16g01630.
DR GeneID; 4988556; -.
DR KEGG; ang:An16g01630; -.
DR VEuPathDB; FungiDB:An16g01630; -.
DR HOGENOM; CLU_026673_16_5_1; -.
DR OrthoDB; 2688376at2759; -.
DR Proteomes; UP000006706; Chromosome 5R.
DR GO; GO:0016651; F:oxidoreductase activity, acting on NAD(P)H; IEA:InterPro.
DR CDD; cd08249; enoyl_reductase_like; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR047122; Trans-enoyl_RdTase-like.
DR PANTHER; PTHR45348; HYPOTHETICAL OXIDOREDUCTASE (EUROFUNG); 1.
DR PANTHER; PTHR45348:SF2; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C2E1P3.01; 1.
DR Pfam; PF08240; ADH_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAK42780.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 15..341
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 343 AA; 36616 MW; D1C170E01742101C CRC64;
MTQNKAAWIT APTEHPFTIR DAPYPTPGPG EIVIKNAAVS INPADWKIQT YGGPWLRNWP
FVLGTDVAGV VVDVGPGVVR FTKGQRVVAY CHCLGTGDPA NSGFQLYTLV KEITVAGIPD
SITFEEASVL PQAISTAAAG LFLKESLNLP IPPPTGAKPT GKSILIWGGA SSVGATTIQF
AEAAGLSAIT TASTHNHGLV KSLGASAVFD YKSPTIVEDV ASAIRNTDFI GVYDAISEPA
SFEMVRAVLD RLKADVKTIC VSPYDKPTER FAPIFISSNF LTYDSNKHVA DGIWRDFVSE
ALENRRLKPK PDPEVVGKGL EEIQNAVDIL KKGVSAKKII VTL
//
