ID A2RAU0_ASPNC Unreviewed; 383 AA.
AC A2RAU0;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Contig An18c0150, genomic contig {ECO:0000313|EMBL:CAK43236.1};
DE EC=5.5.-.- {ECO:0000313|EMBL:CAK43236.1};
GN ORFNames=An18g04330 {ECO:0000313|EMBL:CAK43236.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK43236.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK43236.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; AM270407; CAK43236.1; -; Genomic_DNA.
DR RefSeq; XP_001398892.1; XM_001398855.1.
DR AlphaFoldDB; A2RAU0; -.
DR EnsemblFungi; CAK43236; CAK43236; An18g04330.
DR GeneID; 4989998; -.
DR KEGG; ang:An18g04330; -.
DR VEuPathDB; FungiDB:An18g04330; -.
DR HOGENOM; CLU_030273_3_2_1; -.
DR OrthoDB; 1691455at2759; -.
DR Proteomes; UP000006706; Chromosome 8L.
DR GO; GO:0008869; F:galactonate dehydratase activity; IDA:AspGD.
DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR GO; GO:0016052; P:carbohydrate catabolic process; IDA:AspGD.
DR GO; GO:0034194; P:D-galactonate catabolic process; IEA:InterPro.
DR CDD; cd03325; D-galactonate_dehydratase; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR034593; DgoD-like.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR023592; Galactonate_deHydtase.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR PANTHER; PTHR48080:SF2; D-GALACTONATE DEHYDRATASE; 1.
DR PANTHER; PTHR48080; D-GALACTONATE DEHYDRATASE-RELATED; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDF00003; D-galactonate_dehydratase; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
PE 4: Predicted;
KW Isomerase {ECO:0000313|EMBL:CAK43236.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 126..228
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
SQ SEQUENCE 383 AA; 42577 MW; FC946DAE785229DC CRC64;
MVKIKSIEYF RVPPRWLFVK IVDEDGQCGW GESTLEGHTE AVEGTLNALC KRFQGYEADD
IEHIWQMAWR LGFYRGGPVF MSAISGIDIA LWDLKGRRLG VPIYQLLGGK VRNKLSVYAW
IGGDRPSDVE AAGKARLAQG FKAIKMNATE DINWLDSPRA LDSSVERLKT VKALGLDAAL
DFHGRLHKPM AKQLAKALEP HRPLFLEEPL LSEHPEAIKQ LSDQVSCPIA LGERLYSRWD
VKRFLEDASV DILQPDIAHC GGISELRRIA SMAETYDVAI APHCPLGSIA LAACMQVDLA
TPNFVIQEMS LGMHYNTEAG EYDITSYVKD PSVFAVKDGY VDALTAPGLG IEVNEELVRQ
LAVNSEPWPP KEFFGPDGGI REW
//
