ID A2RH95_LACLM Unreviewed; 644 AA.
AC A2RH95;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 108.
DE SubName: Full=Transcriptional regulator mtl operon mtlR {ECO:0000313|EMBL:CAL96631.1};
GN Name=mtlR {ECO:0000313|EMBL:CAL96631.1};
GN OrderedLocusNames=llmg_0023 {ECO:0000313|EMBL:CAL96631.1};
OS Lactococcus lactis subsp. cremoris (strain MG1363).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus; Lactococcus cremoris subsp. cremoris.
OX NCBI_TaxID=416870 {ECO:0000313|EMBL:CAL96631.1, ECO:0000313|Proteomes:UP000000364};
RN [1] {ECO:0000313|EMBL:CAL96631.1, ECO:0000313|Proteomes:UP000000364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MG1363 {ECO:0000313|EMBL:CAL96631.1,
RC ECO:0000313|Proteomes:UP000000364};
RX PubMed=17307855; DOI=10.1128/JB.01768-06;
RA Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C.,
RA Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P.,
RA van Sinderen D., Kok J.;
RT "The complete genome sequence of the lactic acid bacterial paradigm
RT Lactococcus lactis subsp. cremoris MG1363.";
RL J. Bacteriol. 189:3256-3270(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AM406671; CAL96631.1; -; Genomic_DNA.
DR RefSeq; WP_011834135.1; NZ_WJVF01000016.1.
DR AlphaFoldDB; A2RH95; -.
DR SMR; A2RH95; -.
DR STRING; 416870.llmg_0023; -.
DR KEGG; llm:llmg_0023; -.
DR eggNOG; COG3711; Bacteria.
DR HOGENOM; CLU_013442_2_2_9; -.
DR OrthoDB; 9776005at2; -.
DR PhylomeDB; A2RH95; -.
DR Proteomes; UP000000364; Chromosome.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.1790.10; PRD domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR013199; HTH_Mga_DNA-bd_dom.
DR InterPro; IPR007737; Mga_HTH.
DR InterPro; IPR011608; PRD.
DR InterPro; IPR036634; PRD_sf.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR InterPro; IPR002178; PTS_EIIA_type-2_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30185; CRYPTIC BETA-GLUCOSIDE BGL OPERON ANTITERMINATOR; 1.
DR PANTHER; PTHR30185:SF18; TRANSCRIPTIONAL REGULATOR MTLR; 1.
DR Pfam; PF08280; HTH_Mga; 1.
DR Pfam; PF05043; Mga; 1.
DR Pfam; PF00874; PRD; 1.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
DR SUPFAM; SSF63520; PTS-regulatory domain, PRD; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51372; PRD_2; 1.
DR PROSITE; PS51094; PTS_EIIA_TYPE_2; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 278..382
FT /note="PRD"
FT /evidence="ECO:0000259|PROSITE:PS51372"
FT DOMAIN 486..634
FT /note="PTS EIIA type-2"
FT /evidence="ECO:0000259|PROSITE:PS51094"
SQ SEQUENCE 644 AA; 74550 MW; 1B024294BB471167 CRC64;
MFLTSREQKL IHTFLKRGTL TISEMMEITG TSRRTLYRDL NNLQKSLPEE ISLQTSEEGY
FIKGDIKQLS QAHELVEYTM TERLYGEILL LIENRASILS LTDYFGISQP TVTNDLRQLE
QTLIENEISL IRERGLKIEG LEENIRSVFV AAIYNSASLQ ELISNQLSDN KLLSILDLDK
FKQAYDAFES LILPEDMTDK VRVLMELFLV TTLIRIDEGH FITSESLSSP SKGALNFVNK
LLTALSVTKF VVSEITYLAS VYEILYFGFG RELLFMEKFD TDFSYKIRQI IDRVSTKLEI
EFGKDDRLYG LLYAHLKESE MLPILFPKKE NDFIKKIKKD NPEIYKAVNE SLKLIFDKNF
SEMEITFVTL HFVSTLERSD LVLPLRSALV SNRGRISCEF VMSNLRKNFP FLKKIDLIQN
SVKVVKSQYD VIFTTEKEFD YLYINPMLDQ KNLDNIRHQL RHIQQKSRTL TIDSKEQRNF
LNLNDLFTTG NEILSTFEIK TLSNQPKLSD TVKQIAKTVN EDDGELAELI EERFRETHLA
IPETNIALFH AVHSSISSPL FKIYELSQEI EGMAMDHQMI KINRVLLLLA PPEVPEYVSY
LLGKLSSSII ENKLYTRIYD SGNYEIVSEL LREIIIEAVK QYGD
//
