ID A2RRU9_DANRE Unreviewed; 527 AA.
AC A2RRU9;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Neuronal pentraxin receptor {ECO:0000313|RefSeq:NP_001037779.1};
DE SubName: Full=Si:dkeyp-20e4.1 {ECO:0000313|EMBL:AAI31862.1};
GN Name=nptxrb {ECO:0000313|ZFIN:ZDB-GENE-050208-595};
GN Synonyms=nptxr {ECO:0000313|RefSeq:NP_001037779.1}, si:dkeyp-20e4.1
GN {ECO:0000313|EMBL:AAI71437.1, ECO:0000313|RefSeq:NP_001037779.1},
GN zgc:158178 {ECO:0000313|RefSeq:NP_001037779.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955 {ECO:0000313|EMBL:AAI31862.1};
RN [1] {ECO:0000313|EMBL:AAI31862.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo {ECO:0000313|EMBL:AAI31862.1};
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000000437}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=23594743; DOI=10.1038/nature12111;
RG Genome Reference Consortium Zebrafish;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Eliott D.,
RA Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Mortimer B.,
RA Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M.,
RA Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M.,
RA Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J.,
RA Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D.,
RA Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K.,
RA Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R.,
RA Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M.,
RA Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D.,
RA Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M.,
RA Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M.,
RA Woodmansey R., Clark G., Cooper J., Cooper J., Tromans A., Grafham D.,
RA Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J.,
RA Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I.,
RA Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M.,
RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M.,
RA Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B.,
RA Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P.,
RA Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R.,
RA Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I.,
RA Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H.,
RA Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
RN [3] {ECO:0000313|RefSeq:NP_001037779.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=27189481;
RA Pasquier J., Cabau C., Nguyen T., Jouanno E., Severac D., Braasch I.,
RA Journot L., Pontarotti P., Klopp C., Postlethwait J.H., Guiguen Y.,
RA Bobe J.;
RT "Gene evolution and gene expression after whole genome duplication in fish:
RT the PhyloFish database.";
RL BMC Genomics 17:368-368(2016).
RN [4] {ECO:0000313|RefSeq:NP_001037779.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR EMBL; BC131861; AAI31862.1; -; mRNA.
DR EMBL; BC171437; AAI71437.1; -; mRNA.
DR EMBL; BC171439; AAI71439.1; -; mRNA.
DR RefSeq; NP_001037779.1; NM_001044314.1.
DR GeneID; 100005257; -.
DR KEGG; dre:100005257; -.
DR AGR; ZFIN:ZDB-GENE-050208-595; -.
DR CTD; 100005257; -.
DR ZFIN; ZDB-GENE-050208-595; nptxrb.
DR OrthoDB; 3026086at2759; -.
DR Proteomes; UP000000437; Alternate scaffold 22.
DR Proteomes; UP000000437; Chromosome 22.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001759; Pentraxin-related.
DR PANTHER; PTHR19277:SF94; NEURONAL PENTRAXIN RECEPTOR; 1.
DR PANTHER; PTHR19277; PENTRAXIN; 1.
DR Pfam; PF00354; Pentaxin; 1.
DR PRINTS; PR00895; PENTAXIN.
DR SMART; SM00159; PTX; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51828; PTX_2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU01172};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Receptor {ECO:0000313|RefSeq:NP_001037779.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT COILED 261..310
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 348..407
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01172"
SQ SEQUENCE 527 AA; 57870 MW; 0CD7608538007911 CRC64;
MKFVVVIVSA GLLAFLGAVI CIIASVYRRS SAAAPQGLSD NRSLSLLEPL PGSVAHAGPL
GALHGAESYE GGGLDIGLEI PSINELSTGD VTRPSPKQFT LNRLICTPVP LSDCKSRGLR
EQSDDAFAEE EDWSLRTTAE ELRQIVMQQN DQILMDQRTI TELTGKLSEC ENGLEERTLN
ERSMGVWAGG RRHMAGDDVS GSVAVQLQTA RAVEELERAI LQLKDRIEKL EMEIGPAAIN
HTEHTVSTLG SIVVGEPGRP VEDLEGELEK KIRLLEKERK NLRKETQSHH QHIDQGINTL
QERIAELEQS LTDYSYPQGY KLSFPVRTNY MYGLVRRNIP EMYAFTACLW LKPAESGIGT
PFSYAVPEQP NQLVLLQGIH NPAELLINDK VAQLPLSLPK GIWQHICVSW TLRDGVWKAY
QGGKMRGRGD GLSAWHPIKS GGVLVLGQEQ DTLGGRFDAS QALVGELSLF NLWDRVLSPT
EVAALASCAE SPRLGNVVPW TDRDVDVFGG AVKDPVDPCI KSSHPRQ
//
