ID A2RZR7_BURM9 Unreviewed; 872 AA.
AC A2RZR7;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 15-DEC-2009, sequence version 2.
DT 27-MAR-2024, entry version 77.
DE SubName: Full=Sensory box diguanylate cyclase/cyclic diguanylate phosphodiesterase {ECO:0000313|EMBL:ABM99067.2};
GN OrderedLocusNames=BMA10229_1384 {ECO:0000313|EMBL:ABM99067.2};
OS Burkholderia mallei (strain NCTC 10229).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=412022 {ECO:0000313|EMBL:ABM99067.2, ECO:0000313|Proteomes:UP000002283};
RN [1] {ECO:0000313|EMBL:ABM99067.2, ECO:0000313|Proteomes:UP000002283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 10229 {ECO:0000313|EMBL:ABM99067.2,
RC ECO:0000313|Proteomes:UP000002283};
RA DeShazer D., Woods D.E., Nierman W.C.;
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000545; ABM99067.2; -; Genomic_DNA.
DR RefSeq; WP_004190283.1; NC_008835.1.
DR AlphaFoldDB; A2RZR7; -.
DR GeneID; 56598430; -.
DR KEGG; bml:BMA10229_1384; -.
DR HOGENOM; CLU_000445_70_54_4; -.
DR Proteomes; UP000002283; Chromosome II.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 92..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..299
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 479..613
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 624..872
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 872 AA; 97382 MW; E7A7173629BCFB31 CRC64;
MASLRTIYTS DSATGHASGI WRRTRNGPPP VRFRRWRAPG KYETAATKRR GGGAEARWTM
NGTSSMREQA LGMNDGGGQA AELRPALDVW PILLMVSVLV CVVIVSLAVV SFLRVYIGGE
STWSKSQKDA VIYLIRYAET GDERAYKLYE AAIDKPYRLS LARAALQRKP PDRASAREAI
IASGIDPTDA TAAALLLPAL SWVAKINYAL QCWMQADVEL AEFRSVASQL HALVSSGHRD
DARVKALEYR AWEINERVSG LPDRFSKAFS DEFRSSVALL LVCYFVASMF LMYLALVWAR
KAALQRLSIQ YALDRSEAFA EAALSSVAEA VITVGLAKNV DFINNAAEQL LGYPAAACVG
APVSSVLMLL DKETGHAVDI VDEFWAREER TPIKREVHLL RRDHSKIVVQ TTISEMGDRV
HGHIGYVLIL RNMTREQQFL ESLAWQATHD VLTGLVNRVE FERRLEIALA DTASGKERAD
SMLLMLDLDR FKEINDTCGH AAGDAMLREV TQRFQSCLDD DDVLARLGGD EFGVLLPHGA
GSWPSKNKAE RLRRSLEDFV FLWEGERFTV SVSIGVLELC KAPRNLEMAV KLADIACYIA
KERGRNRIQL ADPSDLQQAR HVGDVQWSRR IKTALENDGF RLYVQPIVHT RPDSRTPERA
EVLLRMMDSA GRDISPAAFL PAAERYGLMG LIDRWVIRTV FRKLSALPAR EYHEYNVNLS
GASISDERFL EFVIAELLSS GLEPSVICFE ITETIAVKNL ELASRFMGEL RTIGCRFALD
DFGAGMSSFR YLRSLPIDYL KIDGEFVSNM MSDRVSYGVV SAINEVAHSM RCSTVAEHVE
SEVELAMLRE LGIDFCQGYF FAQPSPWREG GY
//
