ID   A2S3V2_BURM9            Unreviewed;       493 AA.
AC   A2S3V2;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 87.
DE   SubName: Full=Transcriptional regulator, GntR family {ECO:0000313|EMBL:ABN02010.1};
GN   OrderedLocusNames=BMA10229_A0626 {ECO:0000313|EMBL:ABN02010.1};
OS   Burkholderia mallei (strain NCTC 10229).
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=412022 {ECO:0000313|EMBL:ABN02010.1, ECO:0000313|Proteomes:UP000002283};
RN   [1] {ECO:0000313|EMBL:ABN02010.1, ECO:0000313|Proteomes:UP000002283}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCTC 10229 {ECO:0000313|EMBL:ABN02010.1,
RC   ECO:0000313|Proteomes:UP000002283};
RA   DeShazer D., Woods D.E., Nierman W.C.;
RL   Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family.
CC       {ECO:0000256|ARBA:ARBA00005384}.
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DR   EMBL; CP000546; ABN02010.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2S3V2; -.
DR   KEGG; bml:BMA10229_A0626; -.
DR   HOGENOM; CLU_017584_0_0_4; -.
DR   Proteomes; UP000002283; Chromosome I.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd00609; AAT_like; 1.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR42790; AMINOTRANSFERASE; 1.
DR   PANTHER; PTHR42790:SF9; GNTR FAMILY REGULATORY PROTEIN-RELATED; 1.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          3..71
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50949"
SQ   SEQUENCE   493 AA;  54188 MW;  392FE2B9EC76D6C2 CRC64;
     MSMKRYETLA RAMADDIRSG NITTGTRMPS LRQMIAQHRV SQSTVFRAYY LLEQWGLIRA
     RERSGYYVAH GAQASVRANG MNGMNGAHAT QDGRLTRDAA PAESRKVDIS DLVFSVLEAA
     THPRIVPLGS AFASPHLFPL PRLAKSLAQA ARLVSPWSAV VDLPPGSEQL RRQIALRYLG
     IGVSQPIDEI VVTNGALEAL NLCLTAVTRP GDVVAVEAPG FYAALQAIER LDLRAVEIPV
     DPRTGLDLDA LAAALERHDV RACWFMTNFQ NPTGVTLSAD KKKALVDMLA AREVPLIEDD
     VYGELHHGPD YPLPARAFDK HGLVMHCSSF SKTLAPGYRI GWAAAGRFAE KVQRLKLMTT
     LSASIPAQVG IADYLEHGGY DRHLRKLRGA LRGQMERMND ALMRHLPPDV HWTLPDGGYF
     VWLEFPDAID AMGLHREAIR RGVSVAPGPL FSAAHAFERC VRINFGHPWS AAVDDAIRTV
     GELVAQPSVR KRR
//