ID A2S6C7_BURM9 Unreviewed; 513 AA.
AC A2S6C7;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=RNA polymerase sigma-54 factor {ECO:0000256|PIRNR:PIRNR000774};
GN Name=rpoN {ECO:0000313|EMBL:ABN01372.1};
GN OrderedLocusNames=BMA10229_A1514 {ECO:0000313|EMBL:ABN01372.1};
OS Burkholderia mallei (strain NCTC 10229).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=412022 {ECO:0000313|EMBL:ABN01372.1, ECO:0000313|Proteomes:UP000002283};
RN [1] {ECO:0000313|EMBL:ABN01372.1, ECO:0000313|Proteomes:UP000002283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC 10229 {ECO:0000313|EMBL:ABN01372.1,
RC ECO:0000313|Proteomes:UP000002283};
RA DeShazer D., Woods D.E., Nierman W.C.;
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|PIRNR:PIRNR000774}.
CC -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC {ECO:0000256|ARBA:ARBA00008798, ECO:0000256|PIRNR:PIRNR000774}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000546; ABN01372.1; -; Genomic_DNA.
DR AlphaFoldDB; A2S6C7; -.
DR KEGG; bml:BMA10229_A1514; -.
DR HOGENOM; CLU_020569_0_1_4; -.
DR Proteomes; UP000002283; Chromosome I.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR InterPro; IPR000394; RNA_pol_sigma_54.
DR InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR InterPro; IPR038709; RpoN_core-bd_sf.
DR NCBIfam; TIGR02395; rpoN_sigma; 1.
DR PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR Pfam; PF00309; Sigma54_AID; 1.
DR Pfam; PF04963; Sigma54_CBD; 1.
DR Pfam; PF04552; Sigma54_DBD; 1.
DR PIRSF; PIRSF000774; RpoN; 1.
DR PRINTS; PR00045; SIGMA54FCT.
DR PROSITE; PS00717; SIGMA54_1; 1.
DR PROSITE; PS00718; SIGMA54_2; 1.
DR PROSITE; PS50044; SIGMA54_3; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000774};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR000774};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000774}.
FT DOMAIN 148..340
FT /note="RNA polymerase sigma factor 54 core-binding"
FT /evidence="ECO:0000259|Pfam:PF04963"
FT DOMAIN 356..511
FT /note="RNA polymerase sigma factor 54 DNA-binding"
FT /evidence="ECO:0000259|Pfam:PF04552"
FT REGION 81..150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 513 AA; 56220 MW; AD7001FA47A5330D CRC64;
MANFRYESLF AMKASLQLRL SQHLALTPQL QQSIRLLQLS TLELQQEVAT AIAQNPLLEN
DDDWIASPLR VAADGSVIAQ TPASSAPEPM AGAPNGTAAT NERTERDETA GVDEYDSYSA
DGGDASQWNL DDFGRSPAAS DDDDLPPMQI HETSTSLRDH LMAQLRVTQA SPRDRALVTF
LIESLDDDGY LSASLEEVLA DLPAELEVDV DELNAALALV HSFDPAGVGA RSASECLKLQ
LLRLDPSPTR ALALDIVSQH LELLAARDFT RLRKQLKATD DALRDAHALI RSLEPFPGAA
YGKAEADYVV PDIIVKKAGQ NWQAELNPEV VPKLRINNLY ANILRNSRGD PSAGSLKQQL
QEARWLIKNI QQRFETILRV AQAIVERQKN FFAHGEIAMR PLVLREIADT LGLHESTVSR
VTTGKYMLTP FGTLEFKYFF GSHVSTDTGG AASSTAIRAL IKQLIGAEDP KSPLSDSRIA
ELLAEQGFVV ARRTVAKYRE ALKIPAVNLR KSL
//
