ID A2SJJ4_METPP Unreviewed; 330 AA.
AC A2SJJ4;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 85.
DE RecName: Full=geranylgeranyl diphosphate reductase {ECO:0000256|ARBA:ARBA00012380};
DE EC=1.3.1.83 {ECO:0000256|ARBA:ARBA00012380};
DE AltName: Full=Geranylgeranyl reductase {ECO:0000256|ARBA:ARBA00033069};
GN OrderedLocusNames=Mpe_A2779 {ECO:0000313|EMBL:ABM95733.1};
OS Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM95733.1, ECO:0000313|Proteomes:UP000000366};
RN [1] {ECO:0000313|EMBL:ABM95733.1, ECO:0000313|Proteomes:UP000000366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC {ECO:0000313|Proteomes:UP000000366};
RX PubMed=17158667; DOI=10.1128/JB.01259-06;
RA Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA Hristova K.R.;
RT "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT proteobacterium Methylibium petroleiphilum PM1.";
RL J. Bacteriol. 189:1931-1945(2007).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3 NADP(+) + phytyl diphosphate = geranylgeranyl diphosphate +
CC 3 H(+) + 3 NADPH; Xref=Rhea:RHEA:26229, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57533, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349,
CC ChEBI:CHEBI:75434; EC=1.3.1.83;
CC Evidence={ECO:0000256|ARBA:ARBA00001640};
CC -!- PATHWAY: Porphyrin-containing compound metabolism.
CC {ECO:0000256|ARBA:ARBA00023444}.
CC -!- SIMILARITY: Belongs to the geranylgeranyl reductase family. ChlP
CC subfamily. {ECO:0000256|ARBA:ARBA00006632}.
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DR EMBL; CP000555; ABM95733.1; -; Genomic_DNA.
DR RefSeq; WP_011830362.1; NC_008825.1.
DR AlphaFoldDB; A2SJJ4; -.
DR STRING; 420662.Mpe_A2779; -.
DR KEGG; mpt:Mpe_A2779; -.
DR eggNOG; COG0644; Bacteria.
DR HOGENOM; CLU_024648_3_0_4; -.
DR Proteomes; UP000000366; Chromosome.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0102067; F:geranylgeranyl diphosphate reductase activity; IEA:UniProtKB-EC.
DR GO; GO:0045550; F:geranylgeranyl reductase activity; IEA:InterPro.
DR GO; GO:0015995; P:chlorophyll biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0015979; P:photosynthesis; IEA:UniProtKB-KW.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR010253; BchP_ChlP_pln/prok.
DR InterPro; IPR002938; FAD-bd.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR011777; Geranylgeranyl_Rdtase_fam.
DR NCBIfam; TIGR02023; BchP-ChlP; 1.
DR NCBIfam; TIGR02032; GG-red-SF; 1.
DR PANTHER; PTHR42685; GERANYLGERANYL DIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR42685:SF4; GERANYLGERANYL DIPHOSPHATE REDUCTASE, CHLOROPLASTIC; 1.
DR Pfam; PF01494; FAD_binding_3; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW Chlorophyll biosynthesis {ECO:0000256|ARBA:ARBA00023171};
KW Photosynthesis {ECO:0000256|ARBA:ARBA00022531};
KW Reference proteome {ECO:0000313|Proteomes:UP000000366}.
FT DOMAIN 21..227
FT /note="FAD-binding"
FT /evidence="ECO:0000259|Pfam:PF01494"
SQ SEQUENCE 330 AA; 36477 MW; D2AE41D2F26FC433 CRC64;
MVSPTDKRVD IPIENGFVGM VDRDAFDEWL RARAAGSGAQ RQIGSFERLT RDDDGVSVVH
YQARERPGDA ASAPRSVRAR CVIGADGARS AVARQAIAGA ERNPCVFAYH EIVRAPLAKP
VGYDGSRCDV YYRGSLSPDF YGWVFPHGDT LSIGTGSADK GFSLRAAVGR LRSDSGLQGA
QTLRREGAPI PMKPLRRWDN GRDVLLAGDA AGVVAPASGE CIYYAMASGR LAAEAVESAL
QTGDGRCLRQ ARRRFMKAHG TVFRVLGVMQ WFWYSSDRRR ERFVTICEDR DVQQLTFESY
MNKELVRKKP MAHVRIFFKD MGHLLGLVRA
//
