ID A2SPV5_METLZ Unreviewed; 335 AA.
AC A2SPV5;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 24-JAN-2024, entry version 76.
DE SubName: Full=NUDIX hydrolase {ECO:0000313|EMBL:ABN06361.1};
GN OrderedLocusNames=Mlab_0185 {ECO:0000313|EMBL:ABN06361.1};
OS Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX NCBI_TaxID=410358 {ECO:0000313|EMBL:ABN06361.1, ECO:0000313|Proteomes:UP000000365};
RN [1] {ECO:0000313|EMBL:ABN06361.1, ECO:0000313|Proteomes:UP000000365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43576 / DSM 4855 / Z {ECO:0000313|Proteomes:UP000000365};
RX PubMed=21304657; DOI=10.4056.sigs.35575;
RA Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL Stand. Genomic Sci. 1:197-203(2009).
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DR EMBL; CP000559; ABN06361.1; -; Genomic_DNA.
DR RefSeq; WP_011832562.1; NC_008942.1.
DR AlphaFoldDB; A2SPV5; -.
DR STRING; 410358.Mlab_0185; -.
DR GeneID; 25393671; -.
DR KEGG; mla:Mlab_0185; -.
DR eggNOG; arCOG01073; Archaea.
DR HOGENOM; CLU_827978_0_0_2; -.
DR OrthoDB; 104705at2157; -.
DR Proteomes; UP000000365; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0010181; F:FMN binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03424; ADPRase_NUDT5; 1.
DR Gene3D; 3.40.50.360; -; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR008254; Flavodoxin/NO_synth.
DR InterPro; IPR001226; Flavodoxin_CS.
DR InterPro; IPR026816; Flavodoxin_dom.
DR InterPro; IPR029039; Flavoprotein-like_sf.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR PANTHER; PTHR38030; PROTOPORPHYRINOGEN IX DEHYDROGENASE [MENAQUINONE]; 1.
DR PANTHER; PTHR38030:SF2; PROTOPORPHYRINOGEN IX DEHYDROGENASE [QUINONE]; 1.
DR Pfam; PF12724; Flavodoxin_5; 1.
DR Pfam; PF00293; NUDIX; 1.
DR SUPFAM; SSF52218; Flavoproteins; 1.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS00201; FLAVODOXIN; 1.
DR PROSITE; PS50902; FLAVODOXIN_LIKE; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ABN06361.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000365};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3..153
FT /note="Flavodoxin-like"
FT /evidence="ECO:0000259|PROSITE:PS50902"
FT DOMAIN 195..324
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 335 AA; 37539 MW; D9C1160088E5FBA4 CRC64;
MSTVVIYKSK YGSTEQYAKW IAEELGADLK NADHLKLDDL LPYDTIVYGA GVYVGCIAGI
ALIADNYEQL KDKKLIVFTV GLTDPADEKK YDDLLTKNFT WTMKDAVPAF HFRGALDYKK
IGLGNKLMMK KMKIPEANYV SKEQIQPLLK SLGSSKPANK PENTTTKIYD TPRLTIETRH
VHLPNGKDRN YLFVQPVPAV CILPTDETHV YLIKQYRAVI NEYILEVPAG GMDNGSETPL
ECAKRELAEE ARLSAKEFVP KGYVYSTPGF CTEKLWLFEA RGLAPCEDCA RDEDEIIDVV
KVPKAEVFAM IDRGEIVDAK TIALLTRSLA KLNSD
//
