ID A2T9F6_DROMI Unreviewed; 174 AA.
AC A2T9F6;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=Phosphoinositide 3-kinase {ECO:0000313|EMBL:ABN04379.1};
DE Flags: Fragment;
GN ORFNames=GA17984 {ECO:0000313|EMBL:ABN04379.1};
OS Drosophila miranda (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7229 {ECO:0000313|EMBL:ABN04379.1};
RN [1] {ECO:0000313|EMBL:ABN04379.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MSH22 {ECO:0000313|EMBL:ABN04379.1}, and MSH38
RC {ECO:0000313|EMBL:ABN04380.1};
RX PubMed=17179068; DOI=10.1534/genetics.106.064758;
RA Machado C.A., Haselkorn T.S., Noor M.A.;
RT "Evaluation of the genomic extent of effects of fixed inversion differences
RT on intraspecific variation and interspecific gene flow in Drosophila
RT pseudoobscura and D. persimilis.";
RL Genetics 175:1289-1306(2007).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EF041167; ABN04379.1; -; Genomic_DNA.
DR EMBL; EF041168; ABN04380.1; -; Genomic_DNA.
DR AlphaFoldDB; A2T9F6; -.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR PANTHER; PTHR10048:SF118; PI-3 KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ABN04379.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..158
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ABN04379.1"
FT NON_TER 174
FT /evidence="ECO:0000313|EMBL:ABN04379.1"
SQ SEQUENCE 174 AA; 20157 MW; 4E748DF48FAF4A63 CRC64;
AINEFTLSCA GYCVATYVLG VADRHSDNIM VKRNGQLFHI DFGHILGHFK EKFGVRRERV
PFVLTHDFVY VINKGCNDRE AKEFCHFQEL CERAFLTLRK HGCLILSLFS MMISTGLPEL
SSEKDLNYLR DTLVLDYTEE KAREHFRAKF SEALANSWKT SLNWASHNFS KNNK
//
