ID   A2TY27_9FLAO            Unreviewed;       344 AA.
AC   A2TY27;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   24-JAN-2024, entry version 80.
DE   SubName: Full=Pyridoxal phosphate biosynthetic protein PdxA {ECO:0000313|EMBL:EAQ42890.1};
DE            EC=1.1.1.262 {ECO:0000313|EMBL:EAQ42890.1};
GN   Name=pdxA {ECO:0000313|EMBL:EAQ42890.1};
GN   ORFNames=MED152_09210 {ECO:0000313|EMBL:EAQ42890.1};
OS   Polaribacter sp. MED152.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=313598 {ECO:0000313|EMBL:EAQ42890.1, ECO:0000313|Proteomes:UP000006470};
RN   [1] {ECO:0000313|EMBL:EAQ42890.1, ECO:0000313|Proteomes:UP000006470}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MED152 {ECO:0000313|EMBL:EAQ42890.1};
RX   PubMed=17215843; DOI=10.1038/nature05381;
RA   Gomez-Consarnau L., Gonzalez J.M., Coll-Llado M., Gourdon P., Pascher T.,
RA   Neutze R., Pedros-Alio C., Pinhassi J.;
RT   "Light stimulates growth of proteorhodopsin-containing marine
RT   Flavobacteria.";
RL   Nature 445:210-213(2007).
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DR   EMBL; CP004349; EAQ42890.1; -; Genomic_DNA.
DR   RefSeq; WP_015481588.1; NC_020830.1.
DR   AlphaFoldDB; A2TY27; -.
DR   STRING; 313598.MED152_09210; -.
DR   KEGG; pom:MED152_09210; -.
DR   eggNOG; COG1995; Bacteria.
DR   HOGENOM; CLU_040168_4_0_10; -.
DR   OrthoDB; 9801783at2; -.
DR   Proteomes; UP000006470; Chromosome.
DR   GO; GO:0050570; F:4-hydroxythreonine-4-phosphate dehydrogenase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR005255; PdxA_fam.
DR   NCBIfam; TIGR00557; pdxA; 1.
DR   PANTHER; PTHR30004; 4-HYDROXYTHREONINE-4-PHOSPHATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR30004:SF6; D-THREONATE 4-PHOSPHATE DEHYDROGENASE; 1.
DR   Pfam; PF04166; PdxA; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:EAQ42890.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006470}.
SQ   SEQUENCE   344 AA;  37860 MW;  B04EA2E76BB96755 CRC64;
     MDKTDKIIVG ISIGDLNGIG VEVILKTFED KRMLDFCTPV LFGATKAISY HKKTLGLETP
     VHGITSINQI NHNKINVLNI WKEEVKLELG NATKESGNYA FKSLEAAVDH LKENKIDVLV
     TAPINKENIQ SEFFKTPGHT EYLEEKLDGN SLMILMTDEL RIGLITGHIP ISKVAETITP
     ELIKSKVSTM YNSLRKDFGI NKPKIAVLSL NPHCGDNGII GEEDDAIIKP TVTEIAASGM
     LVFGPYAADG FFGSETYKQF DGVLATYHDQ GLAPFKALSF GKGVNFTAGL NHVRTSPDHG
     TGYDIAGKNQ ANPSSFKEAL FTAIQVYRSR EEYKELTQNP LKVR
//