ID   A2W252_9BURK            Unreviewed;       877 AA.
AC   A2W252;
DT   20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   20-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN   ORFNames=BCPG_04421 {ECO:0000313|EMBL:EAY66048.1};
OS   Burkholderia cenocepacia PC184.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=350702 {ECO:0000313|EMBL:EAY66048.1, ECO:0000313|Proteomes:UP000053735};
RN   [1] {ECO:0000313|EMBL:EAY66048.1, ECO:0000313|Proteomes:UP000053735}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PC184 {ECO:0000313|EMBL:EAY66048.1,
RC   ECO:0000313|Proteomes:UP000053735};
RG   The Broad Institute Genome Sequencing Platform;
RA   Birren B., Lander E., Galagan J., Devon K., Nusbaum C., Borowsky M.L.,
RA   Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M.,
RA   Mauceli E., Brockman W., Young S., LaButti K., DeCaprio D., Crawford M.,
RA   Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., White J.,
RA   Larson L., Alvarado L., Kodira C., Zeng Q., Yandava C., Oleary S.,
RA   LiPuma J., Lory S.;
RT   "The Genome Sequence of Burkholderia cenocepacia (strain PC184).";
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CH482378; EAY66048.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2W252; -.
DR   HOGENOM; CLU_009099_0_0_4; -.
DR   Proteomes; UP000053735; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR017841; Hopanoid_biosynth_HpnN.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   NCBIfam; TIGR03480; HpnN; 1.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR   Pfam; PF03176; MMPL; 1.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        18..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        277..296
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        329..347
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        367..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        405..426
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        716..737
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        749..770
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        776..796
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        808..828
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        840..859
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          304..428
FT                   /note="SSD"
FT                   /evidence="ECO:0000259|PROSITE:PS50156"
SQ   SEQUENCE   877 AA;  92577 MW;  47A1320FBBA117AC CRC64;
     MVTSLIVRLV AWSVRRPVWV VVLSLVIAAF SGVYVAQHFK INTDISKLVD AEPQWAALSK
     AVDNAFPQRN GTILAVVEAP APEFATAAAH ALTEALRKDA DAGRIGPVAE PGGGPFFEHN
     GLLFLSPQEV ADTTAQLASA RPLVNELAKN PSLTGLATTL STTLGQPLLT GQVKLPAMAK
     LLARSAATVD DVLAGKPAAF SWRALVDNDA PRQPARAFVT VQPVVNYGAL KAGAATSQVI
     RDAARSLDLD KRYGAAVRLT GEQPLADDEF ASVEDGAALN GVLTLLAVLV ILWLALRSKR
     MIGSVLVTLF VGLVVTAALG LAMVGSLNMI SVAFMVLFVG LGVDFSIQYG VKYREERFRD
     ERIDHALIGA AHSMGMPLAL ATAAVAASFF SFIPTAYRGV SELGLIAGVG MFVALLTTLT
     LLPALLRLFA PPGESKTPGF PWLAPVDDYL DRHRKPILIG TLAVVIGALP LLAFLHFDFN
     PLHLKDPNSE SMATLLALKD SPEAAVNDVT LLAPSLAQAE AAAKRLDALP EVGRTTTLST
     FIPADQPAKR AAIATAASEL LPALTQPAAP PATDAQRVAA LKRVSDLLSY AAEDHPGPGA
     AAAQHLSASL AKLAAADSAT RDRAERAFSD TLRIALNQLA ALLQPQDITR ESLPPQIVRD
     WVAPDGHALV QISPKVPKGV DPNDDTMLRR FAKAVKAAEP DATGGPISIL HSADTIINAF
     LHAALWSIIS ITVLLWVTLR RFGDVLRTLV PLLVSGIVTL EMCVVLGMSL NFANIIALPL
     MLGVGVAFKV YFVMAWRAGQ TGLLHSSLTH AVLFSAATTA TAFGSLWLSH HPGTSSMGKL
     LALALTCTLI GAVVFQPVLM GKPRVKRAKN QSQGINE
//