ID A2YZH5_ORYSI Unreviewed; 1176 AA.
AC A2YZH5;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=OsI_30758 {ECO:0000313|EMBL:EAZ08486.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946 {ECO:0000313|EMBL:EAZ08486.1, ECO:0000313|Proteomes:UP000007015};
RN [1] {ECO:0000313|EMBL:EAZ08486.1, ECO:0000313|Proteomes:UP000007015}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11 {ECO:0000313|Proteomes:UP000007015};
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J.,
RA Samudrala R., Wang J., Wong G.K., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM000134; EAZ08486.1; -; Genomic_DNA.
DR AlphaFoldDB; A2YZH5; -.
DR STRING; 39946.A2YZH5; -.
DR EnsemblPlants; BGIOSGA030052-TA; BGIOSGA030052-PA; BGIOSGA030052.
DR Gramene; BGIOSGA030052-TA; BGIOSGA030052-PA; BGIOSGA030052.
DR HOGENOM; CLU_000288_22_4_1; -.
DR OMA; SHAHPKK; -.
DR Proteomes; UP000007015; Chromosome 9.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.1490.310; -; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045381; BRI1_island_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48005; LEUCINE RICH REPEAT KINASE 2; 1.
DR PANTHER; PTHR48005:SF13; SERINE_THREONINE-PROTEIN KINASE DDB_G0278509-RELATED; 1.
DR Pfam; PF20141; Island; 1.
DR Pfam; PF00560; LRR_1; 5.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000007015};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1176
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002651039"
FT TRANSMEM 826..847
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 912..1176
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 941
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1176 AA; 124657 MW; 7F021C3FA806185E CRC64;
MAASPPFMAA AAFLTLVVVL FRAPAPAIAV GEEAAALLAF RRASVADDPD GALASWVLGA
GGANSTAPCS WDGVSCAPPP DGRVAAVDLS GMSLAGELRL DALLALPALQ RLNLRGNAFY
GNLSHAAPSP PCALVEVDIS SNALNGTLPP SFLAPCGVLR SVNLSRNGLA GGGFPFAPSL
RSLDLSRNRL ADAGLLNYSF AGCHGVGYLN LSANLFAGRL PELAACSAVT TLDVSWNHMS
GGLPPGLVAT APANLTYLNI AGNNFTGDVS GYDFGGCANL TVLDWSYNGL SSTRLPPGLI
NCRRLETLEM SGNKLLSGAL PTFLVGFSSL RRLALAGNEF TGAIPVELGQ LCGRIVELDL
SSNRLVGALP ASFAKCKSLE VLDLGGNQLA GDFVASVVST IASLRELRLS FNNITGVNPL
PVLAAGCPLL EVIDLGSNEL DGEIMPDLCS SLPSLRKLLL PNNYLNGTVP PSLGDCANLE
SIDLSFNLLV GKIPTEIIRL PKIVDLVMWA NGLSGEIPDV LCSNGTTLET LVISYNNFTG
SIPRSITKCV NLIWVSLSGN RLTGSVPGGF GKLQKLAILQ LNKNLLSGHV PAELGSCNNL
IWLDLNSNSF TGTIPPQLAG QAGLVPGGIV SGKQFAFLRN EAGNICPGAG VLFEFFGIRP
ERLAEFPAVH LCPSTRIYTG TTVYTFTNNG SMIFLDLSYN GLTGTIPGSL GNMMYLQVLN
LGHNELNGTI PDAFQNLKSI GALDLSNNQL SGGIPPGLGG LNFLADFDVS NNNLTGPIPS
SGQLTTFPPS RYDNNNGLCG IPLPPCGHNP PWGGRPRGSP DGKRKVIGAS ILVGVALSVL
ILLLLLVTLC KLRMNQKTEE VRTGYVESLP TSGTSSWKLS GVREPLSINV ATFEKPLRKL
TFAHLLEATN GFSAETLIGS GGFGEVYKAK LKDGSVVAIK KLIHFTGQGD REFTAEMETI
GKIKHRNLVP LLGYCKIGDE RLLVYEYMKH GSLDVVLHDK AKASVKLDWS ARKKIAIGSA
RGLAFLHHSC IPHIIHRDMK SSNVLLDNNL DARVSDFGMA RLMNALDTHL SVSTLAGTPG
YVPPEYYQSF RCTTKGDVYS YGVVLLELLS GKKPIDPTEF GDNNLVGWVK QMVKENRSSE
IFDPTLTDRK SGEAELYQYL KMHASAWMID PTEGQP
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