ID A3CQF5_STRSV Unreviewed; 242 AA.
AC A3CQF5;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=tRNA (Guanosine-2'-O-)-methyltransferase, TrmH family, putative {ECO:0000313|EMBL:ABN45410.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:ABN45410.1};
GN Name=trmH {ECO:0000313|EMBL:ABN45410.1};
GN OrderedLocusNames=SSA_2037 {ECO:0000313|EMBL:ABN45410.1};
OS Streptococcus sanguinis (strain SK36).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=388919 {ECO:0000313|EMBL:ABN45410.1, ECO:0000313|Proteomes:UP000002148};
RN [1] {ECO:0000313|EMBL:ABN45410.1, ECO:0000313|Proteomes:UP000002148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK36 {ECO:0000313|EMBL:ABN45410.1,
RC ECO:0000313|Proteomes:UP000002148};
RX PubMed=17277061; DOI=10.1128/JB.01808-06;
RA Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P.,
RA Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D.,
RA Paik S., Peterson D.L., Macrina F.L., Buck G.A.;
RT "Genome of the opportunistic pathogen Streptococcus sanguinis.";
RL J. Bacteriol. 189:3166-3175(2007).
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DR EMBL; CP000387; ABN45410.1; -; Genomic_DNA.
DR RefSeq; WP_004192371.1; NC_009009.1.
DR RefSeq; YP_001035960.1; NC_009009.1.
DR AlphaFoldDB; A3CQF5; -.
DR STRING; 388919.SSA_2037; -.
DR KEGG; ssa:SSA_2037; -.
DR PATRIC; fig|388919.9.peg.1933; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_0_1_9; -.
DR OrthoDB; 9794400at2; -.
DR Proteomes; UP000002148; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000313|EMBL:ABN45410.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002148};
KW Transferase {ECO:0000313|EMBL:ABN45410.1}.
FT DOMAIN 6..80
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
SQ SEQUENCE 242 AA; 26311 MW; D5C4DE318EAE5F3F CRC64;
MEKNDIVYGV HAVTEALAAN TGNKLYIQDD LCGKKVDKIK DLAAEKKVSI SWTPKKTLQE
MTDGAVHQGF VLRVAEFAYT DFEVLLKKAE QEDNPLLLIL DGLTDPHNLG SILRTADATN
VAGVIIPKHR AVGVTPVVAK TSTGAIEHIP IARVTNLSQT LDKLKEAGFW IFGTDMQGTP
SHKWNTAGKL ALIIGNEGKG ISSNIKKQVD EMISIPMNGH VQSLNASVAA AILMYEVFRN
RL
//
